The cytoplasmic mucin in Paget cells of extramammary Paget's disease

Localization and Characterization of Anionic Sites in Extramammary Paget's Disease with Cationic Colloidal Gold.

“…Special staining for mucin using alcian blue and colloidal iron, and enzyme digestion studies have shown that both eccrine and apocrine sweat glands express sialomucin [1,6]. Therefore demonstration of sialomucin by conventional mucin staining [4,18] does not determine the direction of differentiation in Paget cells. Positively charged colloidal gold stains anionic sites on the sections embedded in the hydrophilic resins [14,20,24].…”

Cultured Paget Cells Derived from the Involved Skin of a Patient with Extramammary Paget's Disease Had an Extended Life Span

“…Recent advances in histochemistry and immunohistochemistry have assisted in determining the nature of Paget cells in extramammary Paget's disease (1)(2)(3)(4). However, these studies were performed on skip.…”