The cytologic and histologic diagnosis of ureteral fibroepithelial polyp in a dog

Abstract

A 6‐year‐old, intact male, brindled, 30‐Lb English Bulldog presented to the Purdue University Veterinary Teaching Hospital with a recurrent history of hematuria, periuria, and lethargy that responded temporarily to antibiotic therapy. The work‐up included a complete blood count, serum biochemical profile, complete urinalysis, diagnostic imaging (abdominal radiographs and ultrasound with contrast urography), and exploratory laparotomy. The diagnostic imaging findings and subsequent exploratory revealed a unilateral, intraluminal, right‐sided, 3‐cm ureteral mass extending from the proximal ureter into the renal pelvis. Subsequently, a unilateral right‐sided ureteronephrectomy followed by biopsy with cytopathology/cytology (impression smears) and histopathology of the ureteral mass was performed. The cytopathologic interpretation was benign mesenchymal proliferation with mildly atypical urothelial cells. The association of this mass with vascular tissue and a benign nuclear appearance on cytology is similar to reports of fibroepithelial polyps (FEPs) and myxomatous tumors. Histopathology diagnosed the mass as an FEP. Cytopathology proved useful in the presumptive diagnosis of this benign urothelial polyp. To the authors' knowledge, this is the first report using cytopathology to depict and characterize FEPs in veterinary and human medical literature.

Obstrução Ureteral Unilateral Por Neoplasia Mesenquimal Em Um Canino - Relato De Caso

“…Seguindo o mesmo princípio dos autores supracitados, Etzioni et al (2020), descrevem que a hidronefrose é diretamente ou implicitamente mencionada em casos de ureter e rins dilatados subsequentes a bloqueios urinários por crescimento tumoral.…”

Endoscopic treatment of a ureteral inflammatory polyp in a 15-year-old Warmblood gelding

“…They cause ureteral obstruction with consequent clinical symptoms: flank or lower abdominal pain, macroscopic hematuria, irritating bladder symptoms, including frequency and urgency when it protrudes into the bladder (Lam et al 2003, Ludwig et al 2015, Kumar et al 2022, Kim et al 2022). Cases of FP have been described in cats and dogs (Reichle et al 2003, Grant & Troy 2014, Etzioni et al 2020) and in a 4-month-old foal as well (Jones et al 1994).…”

Right-sided ureteral hemangiosarcoma in a paraplegic dog

“…Primary neoplasms in the ureteral region are rare in dogs, and most often benign, including fibropapillomas, fibroepithelial polyps, and transitional cell papillomas [ 10 – 12 ]. Limited reports in dogs describe the occurrence of malignant neoplasms in this region, such as leiomyosarcomas [ 13 , 14 ] and transitional cell carcinomas [ 15 ].…”

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dermis, liver, and right atrium [2][3][4][5]. Less common sites include the retroperitoneum, reproductive system, lung, and urinary system [6][7][8][9].Primary neoplasms in the ureteral region are rare in dogs, and most often benign, including fibropapillomas, fibroepithelial polyps, and transitional cell papillomas [10][11][12]. Limited reports in dogs describe the occurrence of malignant neoplasms in this region, such as leiomyosarcomas [13, 14] and transitional cell carcinomas [15].

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