In order to study the correlation between parameters and performance indicators in the cutting process, the importance of different parameters in performance indicators should be determined. In the present study, the side milling process of titanium alloy by the end milling cutter is considered the research object, and analytic hierarchy process and grey-fuzzy evaluation method are used to evaluate the importance of tool geometric parameters and operating parameters on tool wear rate and material removal rate obtained by FEM method. It is found that applying the average method to remove the parameter level makes each parameter achieve the same result. Therefore, this method should be combined with other data processing methods to resolve the above problem. Finally, the range analysis method is applied to obtain the optimal parameter level of different parameters for each performance indicator. The obtained results show that the helix angle has the highest overall importance value, followed by feed per tooth. And the optimum combination of parameters for tool wear rate and material removal rate is obtained respectively.