The cutaneous manifestations of HIV infection

Garman, Mary; Tyring, Stephen K.

doi:10.1016/s0733-8635(01)00011-0

Cited by 56 publications

(38 citation statements)

References 115 publications

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“…[8] SD was found in 22% of our study patients, in contrast to the study by Sharma et al .,[9] who found a lower prevalence of 4.2% among 200 HIV patients screened. In contrast to the previous reports,[10] the incidence of SD was higher in patients who were on HAART; few of them may be explained by IRD. The prevalence of pigmentary disorder in our study was 6.3%.…”

Section: Discussioncontrasting

confidence: 99%

Pattern of mucocutaneous manifestations in human immunodeficiency virus-positive patients in North India

Kore

Kanwar

Vinay

et al. 2013

Indian J Sex Transm Dis

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Background:Mucocutaneous diseases are among the first-recognized clinical manifestations of acquired immune deficiency syndrome. They function as visual markers in assessing the progression of human immunodeficiency virus (HIV) infection. Given the relative ease of examination of skin, its evaluation remains an important tool in the diagnosis of HIV infection.Objective:To determine the pattern of mucocutaneous manifestations in HIV-positive patients and to correlate their presence with CD4 counts.Materials and Methods:This cross-sectional study included 352 HIV-infected patients seen at PGIMER, Chandigarh, India, over a period of 1 year. The patients were screened for mucocutaneous disorders by an experienced dermatologist. The patients were classified into different stages according to the World Health Organization clinical and immunological staging system.Results:The most prevalent infection was candidiasis, seen in 57 patients (16.2%). Prevalence of candidiasis, dermatophytosis, herpes simplex, herpes zoster, molluscum contagiosum (MC), seborrheic dermatitis, adverse drug reaction, nail pigmentation, xerosis and diffuse hair loss differed statistically according to the clinical stages of HIV infection. There was a statistically significant association between immunological stages of HIV infection and dermatophytosis.Conclusion:Results of our study suggest that mucocutaneous findings occur throughout the course of HIV infection. Dermatoses like MC and dermatophytosis show an inverse relation with CD4 cell count, and these dermatoses can be used as a proxy indicator of advanced immunosuppression to start highly active anti-retroviral therapy in the absence of facilities to carry out CD4 cell count.

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Section: Discussioncontrasting

confidence: 99%

Pattern of mucocutaneous manifestations in human immunodeficiency virus-positive patients in North India

Kore

Kanwar

Vinay

et al. 2013

Indian J Sex Transm Dis

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show abstract

“…Although centrally umbilicated papules are highly suggestive of MCV, similar cutaneous papules can also be seen with fungal infections or bacterial infections, especially in HIV-seropositive individuals (Aftergut and Cockerell, 1999;Garman and Tyring, 2002). It is also possible for cutaneous manifestations of HSV, HPV, and VZV to resemble MCV infections (Hanson and Diven, 2003).…”

Section: Discussionmentioning

confidence: 99%

Identification and genotyping of molluscum contagiosum virus from genital swab samples by real-time PCR and Pyrosequencing

Trama

Adelson

Mordechai

2007

Journal of Clinical Virology

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“…275 A fatal result is much more common in immunocompromised patients. In addition, there may be scattered lesions on the skin and even occasionally in the oral cavity.…”

Section: Epstein-barr Virusmentioning

confidence: 99%

“…275 The inflammatory infiltrate is overlaid by an epidermis showing mild vacuolar change, some exocytosis of lymphocytes, and a rare apoptotic keratinocyte. 275 The inflammatory infiltrate is overlaid by an epidermis showing mild vacuolar change, some exocytosis of lymphocytes, and a rare apoptotic keratinocyte.…”

Section: Seborrheic Dermatitismentioning

confidence: 99%