The current status in gastric cancer: Localization, pathology, and age

Abstract

Şahintürk Y, Taşkoparan M, Uyar S, et. al. The current status in gastric cancer: localization, pathology, and age. Endoscopy Gastrointestinal 2016;24:61-64. kanserlerin yaklaşık %50'sinin kardiya ya da fundus kaynaklı olduğu bildirilmiştir (3).Çalışmalarda PGK'nın distal gastrik kansere (DGK) göre daha kötü prognoza sahip olduğu gösterilmiş ve bu durum PGK'nin farklı klinik ve biyolojik davranış göstermesine bağlanmıştır (4). Özellikle obezitenin (3,5) ve sigara kullanımının (6,7) GİRİŞMide kanseri kanser nedenli ölümler arasında ikinci sıradadır. Gelişmiş ülkelerde son yıllarda sıklığı azalma eğilimi gösterse de gelişmekte olan ülkelerde ve mide kanserinin endemik olduğu ülkelerde görülme sıklığı artmaktadır. Son 30 yılda yapılan bir çok çalışmada proksimal gastrik kanser (PGK) insidansında artış olduğu bildirilmiştir (1,2). Amerikan ulusal kanser verileri de bu durumu destekler niteliktedir ve gastrik Background and Aims: Gastric cancer is the second most common cancer-related cause of death throughout the world. It is reported that in recent years, proximal gastric cancer cases have increased, and distal gastric cancer cases have decreased in western countries. We searched for the newly-diagnosed gastric cancer cases between 2010 and 2015 in order to determine the localization, pathology, and age status of the patients. Materials and Methods: Gastric cancer cases diagnosed between 2010 and 2015 in the Antalya Training and Research Hospital and the Ankara Güven Hospital were retrospectively evaluated. A total of 203 patients were included in the study. The patients were divided into two groups according to the year of diagnosis, the first group being diagnosed between 2010 and 2013 and the second one, between 2013 and 2016. These two groups were compared according to the localization and pathology of the tumor and the age of the patients. Results: From the total, 126 (62.1%) patients were male, and 77 (37.9%) were female. There was no statistically significant difference between the mean age of the male and female patients (p > 0.05). A total of 203 patients were studied and 68 (33.5%) were diagnosed as having proximal and 135 (66.5%) as having distal gastric cancer.[Editor1][J2] Proximal gastric cancer cases were more frequent in the second group, but this was not statistically significant. The age and sex showed no difference according to the localization of the gastric cancer (p > 0.05). 154 (75%) adenocancer, 25 (12%) carcinoid tumor, 15 (8%) lymphoma, and 9 (5%) stromal tumor cases were detected. Carcinoid tumor cases were more frequent in the second group, but this was not statistically significant. The age and sex showed no difference according to the pathological type of the gastric cancer (p > 0.05). The rate of stomach cancer under the age of 45 constituted 13.5% of all of the patients. Conclusion: Gastric cancer is mostly seen in the corpus, then in the antrum, and least in the cardia. Our results are inconsistent with the recent studies showing a proximal gastric cancer dominancy, but we showed ...