The Curability of Breast Cancer

Brinkley, Diana; Haybittle, J. L.

doi:10.1016/s0140-6736(75)90003-3

Cited by 158 publications

(28 citation statements)

References 4 publications

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“…Recently they reported a further analysis of the series with survival data to 25 years, which seemed to show that parallelism of the observed and expected survival curves might be evident after 21 years. 3 They noted, however, that the probability of long-term survivors dying of breast cancer continued to be much greater than in the normal population.…”

Section: Introductionmentioning

confidence: 99%

The curability of breast cancer.

Duncan¹,

Kerr²

1976

BMJ

113

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SummaryThe age-correlated survival rates for 982 women treated for localised breast cancer were analysed retrospectively. Analysis by size of the primary cancer showed that those with smaller cancers had a significantly higher survival rate and a significantly reduced probability of dying of cancer. Cured groups of patients were identified for all but those with the smallest tumours-2-0 cm in diameter or smaller. A longer period of follow-up (to 25 years) is necessary to establish the presence of a large cured group in such cases.

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Section: Introductionmentioning

confidence: 99%

The curability of breast cancer.

Duncan¹,

Kerr²

1976

BMJ

113

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“…In 13 instances, signs compatible with locally recurrent disease were found by a clinician in asymptomatic patients at routine follow up; 9 of these cases proved to be benign and 4 malignant. Asymptomatic disseminated disease was found on 3 occasions by routine tests ( (Brinkley & Haybittle 1975). The annual death rate thereafter among survivors remains at 5-12% (Langlands et al 1975).…”

Section: Patients and Resultsmentioning

confidence: 99%

Is Follow up of Patients after Surgery for Breast Cancer Worthwhile?

1985

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The effectiveness of routine outpatient follow up in detecting recurrent disease after ‘curative’ surgery for breast cancer has been evaluated in a retrospective study of 148 patients. In all, 32 patients developed recurrent cancer. In 3 cases, asymptomatic disease was discovered by routine X-rays. In 25 cases, the patient noticed local disease or complained of symptoms due to distant spread, and over half of these returned to the clinic before the next routine appointment. In only 4 cases was routine examination by a doctor solely responsible for the discovery of recurrent disease. It is concluded that routine follow up made little contribution to the welfare of these patients.

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“…Routine radiological skeletal surveys are not sufficiently useful to justify the demand made on X-ray facilities. Patients with small tumours (T 1-2, N 0-1) have a very low pick-up rate for metastases (Citrin et al, 1975;Roberts et al, 1976) whereas 20-40 per cent of this group are positive on isotopic scintigraphy. Nearly all of these scan 'hot spots' become overt metastases in time and influence prognosis (Galasko, 1975a).…”

Section: Tumour Diagnosis and Assessmentmentioning

confidence: 99%