The crystal structure of grisorixin silver salt

Alléaume, M.; Hickel, D.

doi:10.1039/c29700001422

Cited by 17 publications

(4 citation statements)

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“…Therefore, our results show that, unlike the case of neutral depsipeptide valinomycin (19)(20)(21), which complexes metals with a greatly changed conformation, the lasalocid molecule undergoes only minor changes in conformation on complex formation to sodium ions. This finding is consistent with results obtained previously for both monensin (22,23) and grisorixin (24,25).…”

supporting

confidence: 94%

Monomeric Forms of the Acid Ionophore Lasalocid A (X-537A) from Polar Solvents

Chiang

Paul

1977

Science

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supporting

confidence: 94%

Monomeric Forms of the Acid Ionophore Lasalocid A (X-537A) from Polar Solvents

Chiang

Paul

1977

Science

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“…Its crystal structure was determined by X-ray analysis of its thallium and silver salts [99, 100]. Grisorixin showed activity against Gram-positive bacteria, but was shown to be toxic.…”

Section: Structures and Biological Properties Of Several Ionophoresmentioning

confidence: 99%

Structures and Properties of Naturally Occurring Polyether Antibiotics

Rutkowski

Brzeziński

2013

BioMed Research International

105

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Polyether ionophores represent a large group of natural, biologically active substances produced by Streptomyces spp. They are lipid soluble and able to transport metal cations across cell membranes. Several of polyether ionophores are widely used as growth promoters in veterinary. Polyether antibiotics show a broad spectrum of bioactivity ranging from antibacterial, antifungal, antiparasitic, antiviral, and tumour cell cytotoxicity. Recently, it has been shown that some of these compounds are able to selectively kill cancer stem cells and multidrug-resistant cancer cells. Thus, they are recognized as new potential anticancer drugs. The biological activity of polyether ionophores is strictly connected with their molecular structure; therefore, the purpose of this paper is to present an overview of their formula, molecular structure, and properties.

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“…Valinomycingruppe -Valinomycin (l l, 13), Enniatin A, B und C (4,14), Makrotetrolide (15,16,17), Antamanid (18,19,20) und Beauvericin (11) -sind positiv geladen (11); monobasische Säuren der Nigericin-Gruppe -Nigericin (21,22), Monensin (21,23), Grisorixin (24,25), Dianemycin (21,26), X-206 (27), X-537A (28-31) -elektrisch neutral (l 1). Acyclische Antibiotika bauen bei der Komplexbüdung einen Pseudocyclus um das Kation (32).…”

Section: Metallkomplexe Makrocyclischer Neutraler Moleküle Derunclassified

Ammoniumselektive Disk-Elektrode mit dem Carrier-Antibiotikum Nonactin. Verfahren zur kontinuierlichen enzymatischen Elektroanalyse von Harnstoff, I. Mitteilung

Schindler¹,

Schindler²,

Aziz³

1978

Clinical Chemistry and Laboratory Medicine

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Zusammenfassung: Die Membran der beschriebenen ammoniumselektiven Disk-Elektrode besteht aus einer Polyvinylchlorid-Matrix mit der aktiven Phase Nonactin in Tris (2-ethylhexyl)-phosphat und Diphenylether als ioncnselektivem Kunststoff, der einerseits mit der Stirnfläche eines acrylglasummantelten Platin-Drahtes und andererseits mit der Meßflüssigkeit Kontakt hat, wobei sich an dieser Phasengrenze eine Potentialdifferenz ausbilden kann. Ammonium-selective disc-electrode with the carrier-antibiotic nonactin. A method for the continuous enzymatic, electrochemical determination of urea, LSummary: An ammonium-selective disc-electrode is described; the membrane consists of a polyvinylchloride-matrix with an active phase of nonactin in tris (2-ethylhexyl)phosphate and diphenyl ether as the ion-selective plastic. One side of the membrane is in contact with the solution to be measured and the other with the front surface of a platinum wire, which is enclosed in acrylic glass. This arrangement results in a very low drift potential. Einleitung

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The crystal structure of grisorixin silver salt

Cited by 17 publications

References 0 publications

Monomeric Forms of the Acid Ionophore Lasalocid A (X-537A) from Polar Solvents

Monomeric Forms of the Acid Ionophore Lasalocid A (X-537A) from Polar Solvents

Structures and Properties of Naturally Occurring Polyether Antibiotics

Ammoniumselektive Disk-Elektrode mit dem Carrier-Antibiotikum Nonactin. Verfahren zur kontinuierlichen enzymatischen Elektroanalyse von Harnstoff, I. Mitteilung

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