The crystal and molecular structure of deoxyuridine

Rahman, A.; Wilson, H. R.

doi:10.1107/s0567740872005898

Cited by 38 publications

(23 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As in other structures, the O(2)-C(4) bond is slightly longer than the O(2)-C(6) bond. The three types of angle within the furanose ring, C-C-C, C-C-O, C-O-C, have average values of 102.8 ° , 105"5 ° and 108.2 ° respectively, and agree well with those found in the deoxyuridine (Rahman & Wilson, 1972).…”

Section: Description Of the Structure And Discussionsupporting

confidence: 73%

The crystal and molecular structure of 1-methyl-4,5-(D-glucofurano)imidazolidine-2-thione

Jiménez-Garay¹,

López-Castro²,

Márquez³

1974

Acta Crystallogr Sect B

View full text Add to dashboard Cite

The crystal structure has been determined from three-dimensional X-ray data. The space group is P2~2~21 with four molecules in a unit cell of dimensions a= 21.466 (6), b = 8"804 (4) and e= 5.819 (2) A. The structure was solved by direct methods and refined with anisotropic temperature factors by fullmatrix least-squares procedures. The final R value for 1154 independent reflexions is 0-074. The molecules related by the twofold screw axis are linked by N-H.• -S hydrogen bonds to form a helicoidal packing arrangement. Other hydrogen bonds are present.

show abstract

Section: Description Of the Structure And Discussionsupporting

confidence: 73%

The crystal and molecular structure of 1-methyl-4,5-(D-glucofurano)imidazolidine-2-thione

Jiménez-Garay¹,

López-Castro²,

Márquez³

1974

Acta Crystallogr Sect B

View full text Add to dashboard Cite

show abstract

“…Because H2' is expected at -3.0 ppm in a sytz 2'-deoxyriboside (31), a preference for the anti conformation is apparent. (dUrd and dThd are anri in the crystal state (32,33); of the methylated derivatives only m4Urd has been crystallized and shown to be tinri.)' In the case of m'dUrd and m'd'rhd, methylation has converted the 2-keto oxygen to a methoxyl whose shielding effects in a s~n pyrimidine have not been evaluated.…”

Section: Results and Discussion 'H Rz~lclear Magnetic Resonance Claramentioning

confidence: 99%

A kinetic and nuclear magnetic resonance study of methylated pyrimidine nucleosides

Allore¹,

Queen²,

Blonski³

et al. 1983

Can. J. Chem.

View full text Add to dashboard Cite

Alkylated pyrimidine nucleosides are of interest from the viewpoint of mutagenesis and carcinogenesis. 1H and 13C nmr data are presented for a series of 2′-deoxynucleosides methylated at the O2-, O4-, and N3-positions of the base, and discussed in terms of their physical properties. The pH dependence of the stability of the O2- and O4-methylated 2′-deoxyribosides as well as the corresponding ribosides was examined by 1H nmr and ultraviolet (uv) spectrophotometric methods.

show abstract

“…Valuable contributions towards our understanding of polymer structure are obtained from X-ray studies of the crystal and molecular structures of the component mononucleosides and mononucleotides (1)(2)(3)(4)(5). Recently, highresolution X-ray analyses of several ribose dinucleoside monophosphates, adenylyl-(2',5')-uridine (6), uridylyl-(3',5')-adenosine (UpA) (7,8), guanylyl-(3',5')-cytidine (GpC) (9), and adenylyl-(3',5')-uridine (ApU) (10) as well as of the deoxydinucleotide 5'-phosphoryl thymidylyl-(3',5')-thymidine (d(pTpT1) (1 I), have appeared in the literature.…”

Section: Introductionmentioning

confidence: 99%

Proton Magnetic Resonance Studies of 2′-Deoxythymidine, its 3′- and 5′-Monophosphates and 2′-Deoxythymidylyl-(3′, 5′)-2′ -deoxythymidine in Aqueous Solution

Wood¹,

Hruska²,

Ogilvie³

1974

Can. J. Chem.

View full text Add to dashboard Cite

Proton magnetic resonance studies of 2′-deoxythymidine, its 3′ and 5′-monophosphates and the dideoxynucleoside monophosphate, 2′-deoxythymidylyl-(3′,5′)-2′-deoxythymidine are described. Assignment of the spectral bands are carried out and the derived chemical shift and coupling constant data are discussed in terms of the conformational properties of these molecules. The main conclusion reached is that 3′- and 5′-phosphorylation as well as incorporation into the dinucleoside monophosphate at either the 3′- or 5′-terminus has only slight effects on the conformation of thymidine under the experimental conditions employed.

show abstract

The crystal and molecular structure of deoxyuridine

Cited by 38 publications

References 6 publications

The crystal and molecular structure of 1-methyl-4,5-(D-glucofurano)imidazolidine-2-thione

The crystal and molecular structure of 1-methyl-4,5-(D-glucofurano)imidazolidine-2-thione

A kinetic and nuclear magnetic resonance study of methylated pyrimidine nucleosides

Proton Magnetic Resonance Studies of 2′-Deoxythymidine, its 3′- and 5′-Monophosphates and 2′-Deoxythymidylyl-(3′, 5′)-2′ -deoxythymidine in Aqueous Solution

Contact Info

Product

Resources

About