The crosstalk between mitochondrial quality control and metal-dependent cell death
Qi-yuan Zhou,
Chao Ren,
Jing-yan Li
et al.
Abstract:Mitochondria are the centers of energy and material metabolism, and they also serve as the storage and dispatch hubs of metal ions. Damage to mitochondrial structure and function can cause abnormal levels and distribution of metal ions, leading to cell dysfunction and even death. For a long time, mitochondrial quality control pathways such as mitochondrial dynamics and mitophagy have been considered to inhibit metal-induced cell death. However, with the discovery of new metal-dependent cell death including fer… Show more
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