2018
DOI: 10.1155/2018/2025858
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The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria

Abstract: In 2005, Nigeria changed its antimalarial drug policy to Artemisinin-based Combination Therapies (ACTs) for the treatment of malaria infection, and it is imperative for prescribers to strictly comply with this guideline to harmonize malaria management practices within the country. This study aims to evaluate prescribers' adherence with the National Antimalarial Treatment Guideline (NATG) in the treatment of malaria infections and to describe the determinants of antimalarial drugs coprescription with antibiotic… Show more

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Cited by 8 publications
(7 citation statements)
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“…Based on the total number of 1250 prescriptions containing at least one antimalarial drug, a sampling interval of 5 was calculated and simple balloting was used for the first pick. At the end, a total number of two hundred and fifty (250) prescriptions containing at least one antimalarial drug were selected for the study [21]. All prescriptions that have at least one antimalarial drug in it were selected, while all antimalarial prescriptions for pregnant women were excluded.…”
Section: Data Collectionmentioning
confidence: 99%
“…Based on the total number of 1250 prescriptions containing at least one antimalarial drug, a sampling interval of 5 was calculated and simple balloting was used for the first pick. At the end, a total number of two hundred and fifty (250) prescriptions containing at least one antimalarial drug were selected for the study [21]. All prescriptions that have at least one antimalarial drug in it were selected, while all antimalarial prescriptions for pregnant women were excluded.…”
Section: Data Collectionmentioning
confidence: 99%
“…The emergence of drug resistance, particularly among P. falciparum strains, has been a major contributor to the global burden of malaria in the past three decades [9]. Resistance is the most likely explanation for the doubling of malaria-attributable child mortality in eastern and southern Africa [7,10,11].…”
Section: Introductionmentioning
confidence: 99%
“…Artemisinin-based combination therapy is the rst-line therapy in Nigeria and most malaria endemic countries [11,12). In 2005, Nigeria changed its antimalarial drug policy to artemisinin based combination therapy (ACT) [11]. However, recent gains in reducing the burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins.…”
Section: Introductionmentioning
confidence: 99%
“…The emergence of drug resistance, particularly among P. falciparum strains, has been a major contributor to the global burden of malaria in the past three decades [9]. Resistance is the most likely explanation for the doubling of malaria-attributable child mortality in eastern and southern Africa [10,7,11].…”
Section: Introductionmentioning
confidence: 99%
“…Artemisinin-based combination therapy is the rst-line therapy in Nigeria and most malaria endemic countries [12,11). In 2005, Nigeria changed its antimalarial drug policy to artemisinin based combination therapy (ACT) [11]. However, recent gains in reducing the burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins.…”
Section: Introductionmentioning
confidence: 99%