The critical importance of ovarian angiogenesis

Robinson, Robert

doi:10.1071/rdv25n2_ed

Cited by 5 publications

(2 citation statements)

References 26 publications

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“…Throughout this process, the development of new microvasculature is required for luteal structure and function [ 48 ]. The vascular system develops via two disparate mechanisms known as vasculogenesis and angiogenesis, in which the mechanism of angiogenesis is required for the corpus luteum blood vessel growth [ 49 ]. In the early and mid-luteal phase of the corpus luteum life cycle, the ovarian corpus luteum undergoes a high level of neovascularization in major sites of angiogenesis [ 42 ].…”

Section: The Likelihood Of a Novel Role Of Ras In The Ovarian Corpus Luteummentioning

confidence: 99%

The Role of the Guanosine Nucleotide-Binding Protein in the Corpus Luteum

Billhaq

Lee

2021

Animals

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The corpus luteum is a temporary endocrine gland in the ovary. In the ovarian cycle, repeated patterns of specific cellular proliferation, differentiation, and transformation occur that accompany the formation and regression of the corpus luteum. Molecular mechanism events in the ovarian microenvironment, such as angiogenesis and apoptosis, are complex. Recently, we focused on the role of RAS protein in the ovarian corpus luteum. RAS protein plays a vital role in the modulation of cell survival, proliferation, and differentiation by molecular pathway signaling. Additionally, reproductive hormones regulate RAS activity in the cellular physiological function of ovarian follicles during pre-ovulatory maturation and ovulation. Thus, we have reviewed the role of RAS protein related to the biological events of the corpus luteum in the ovary.

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Section: The Likelihood Of a Novel Role Of Ras In The Ovarian Corpus Luteummentioning

confidence: 99%

The Role of the Guanosine Nucleotide-Binding Protein in the Corpus Luteum

Billhaq

Lee

2021

Animals

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“…This cyclic development makes the ovaries one of the few organs with active adult angiogenesis and vascular remodeling under physiological conditions (2)(3)(4). Although angiogenesis-related remodeling and the reconstitution of adult ovarian blood vessels are crucial for the regulation of female reproduction (5), a detailed model of this unique process has not been well described.…”

Section: Introductionmentioning

confidence: 99%