The critical impact of traumatic muscle loss on fracture healing: Basic science and clinical aspects
Maryam Rahmati,
Max Haffner,
Mark A. Lee
et al.
Abstract:Musculoskeletal trauma, specifically fractures, is a leading cause of patient morbidity and disability worldwide. In approximately 20% of cases with fracture and related traumatic muscle loss, bone healing is impaired leading to fracture nonunion. Over the past few years, several studies have demonstrated that bone and the surrounding muscle tissue interact not only anatomically and mechanically but also through biochemical pathways and mediators. Severe damage to the surrounding musculature at the fracture si… Show more
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