The Critical Blood-Sparing Effect of Tranexamic Acid (TXA) in Liposuction: A Systematic Review and Meta-Analysis

Reinhardt, Myrna Eliann; Mutyala, Sudeep; Gerald, Mykal; Zhao, Huaqing; Nova, Vitalina; Cambronero, Sthefano Araya; Patel, Sameer H.; Baltodano, Pablo A.

doi:10.1016/j.jpra.2023.01.002

Cited by 3 publications

(2 citation statements)

References 23 publications

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“… 36 As of July 20, 2023, Florida has implemented bill HB 1471, which requires the use of US guidance for gluteal fat grafting procedures to enhance patient safety. 28 The survey results present a striking contrast between the recommendations for US use particularly in gluteal AFG and its actual implementation in practice. Potential reasons could include the cost of purchasing US equipment, increased surgical time, the need for constant assistance, and the learning curve associated with its usage, as highlighted by Cansancao et al 36 …”

Section: Discussionmentioning

confidence: 88%

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Contemporary Prophylactic Antibiotic Practices and Adjunct Therapies in Autologous Fat Grafting Procedures: A Survey of The Aesthetic Society Members

Araya,

Chang,

Moss

et al. 2024

Aesthetic Surgery Journal Open Forum

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Background Autologous fat grafting (AFG) is a widely used surgical technique that involves extracting a patient's own adipose tissue and transferring it to different areas of the body. The practice is still evolving. Guidelines for antibiotic prophylaxis and use of adjuncts in plastic surgery are currently limited, with a notable absence of standardized guidelines for AFG. Objectives This survey assesses contemporary antibiotic practices and adjuncts in AFG procedures. Methods A 52-question survey was emailed to 3,106 active members of The Aesthetic Society. 293 responses were recorded representing a 9% response rate. Results We analyzed 288 responses. The most common AFG procedures were facial (38%), gluteal (34%), and breast (27%) augmentation. Preoperative antibiotics were used by 84.0% overall, with rates of 74.3%, 88.0%, and 92.7% in face, breast, and gluteal AFG, respectively. Lipoaspirate-antibiotic mixing was reported by 19.8%, mainly during gluteal AFG (46.9%), and less so in face (2.8%) and breast (8%) AFG. Notably, 46.9% of surgeons administered prolonged prophylaxis for 72 hours or more. TXA was utilized by 39.9% of surveyed surgeons. Platelet-Rich Plasma (PRP) was used by 5.6%. Doppler ultrasound (DUS) was incorporated by 16.7% in AFG, with 21.5% in gluteal AFG, 14% in face, and 19% in breast procedures. Conclusions This survey offers insights into antibiotic practices and adjunct therapies in AFG, especially intraoperative antibiotic mixing. Practices among members of The Aesthetic Society vary from guidelines. It is crucial to standardize practices and conduct further research to pave the way for evidence based guidelines in AFG.

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Section: Discussionmentioning

confidence: 88%

“… 27 Our group's systematic review further supports TXA's blood-saving effects during liposuction and fat grafting. 28 …”

Section: Discussionmentioning

confidence: 99%