The CRAC cohort model: A computerized low cost registry of interventional cardiology with daily update and long-term follow-up

Rangé, Gregoire; Chassaing, Stéphan; Marcollet, Pierre; Saint‐Etienne, Christophe; Dequenne, Philippe; Goralski, M.; Bardiére, P.; Beverilli, F.; Godillon, Lucile; Sabine, B.; Carcaillon, Laure; Gautier, S.; Hakim, R.; Albert, Franck; Angoulvant, Denis; Grammatico‐Guillon, Leslie

doi:10.1016/j.respe.2018.01.135

Cited by 22 publications

(21 citation statements)

References 20 publications

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“…Out‐of‐hospital, clinical, and procedural data are collected prospectively by cardiologists at the time of the patient's admission to ICC and recorded in electronic reporting software (CardioReport; CVX Medical, Croissy‐Beaubourg, France). The data are of high quality, 99.6% of completeness and with 89% of consistency 6 . The registry is registered with clinicaltrials.org (NCT02778724).…”

Section: Methodsmentioning

confidence: 99%

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Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry

et al. 2020

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Objectives: The aim of this study was to assess the impact of the coronavirus disease 2019 (COVID-19) outbreak on incidence, delays, and outcomes of ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI) in France. Methods: We analyzed all patients undergoing PPCI <24 hours STEMI included in the prospective France PCI registry. The 2 groups were compared on mean monthly

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Section: Methodsmentioning

confidence: 99%

“…99.6% of completeness and with 89% of consistency. 6 The registry is registered with clinicaltrials.org (NCT02778724).…”

Section: Registry Designmentioning

confidence: 99%

Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry

et al. 2020

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“…The CRAC France PCI Prospective Multicentre registry, 12 started on 1 January 2014, includes all patients undergoing coronary angiography or coronary angioplasty at an interventional cardiology centre (ICC) in the Centre-Val de Loire (CVL) region in central France. The CVL region covers an area of 39,151 km 2 ( Figure 1) with 2.5 million inhabitants and 38 private and public hospitals.…”

Section: Registry Design and Study Populationmentioning

confidence: 99%

Does helicopter transport delay prehospital transfer for STEMI patients in rural areas? Findings from the CRAC France PCI registry

Hakim

Revue

Etienne

et al. 2020

European Heart Journal. Acute Cardiovascular Care

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Aims: The aim of this study was to analyse delays in emergency medical system transfer of ST-segment elevation myocardial infarction (STEMI) patients to percutaneous coronary intervention (PCI) centres according to transport modality in a rural French region. Methods and results: Data from the prospective multicentre CRAC / France PCI registry were analysed for 1911 STEMI patients: 410 transferred by helicopter and 1501 by ground transport. The primary endpoint was the percentage of transfers with first medical contact to primary percutaneous coronary intervention within the 90 minutes recommended in guidelines. The secondary endpoint was time of first medical contact to primary percutaneous coronary intervention. With helicopter transport, time of first medical contact to primary percutaneous coronary intervention in under 90 minutes was less frequently achieved than with ground transport (9.8% vs. 37.2%; odds ratio 5.49; 95% confidence interval 3.90; 7.73; P<0.0001). Differences were greatest for transfers under 50 km (13.7% vs. 44.7%; P<0.0001) and for primary transfers (22.4% vs. 49.6%; P<0.0001). The median time from first medical contact to primary percutaneous coronary intervention and from symptom onset to primary percutaneous coronary intervention (total ischaemic time) were significantly higher in the helicopter transport group than in the ground transport group (respectively, 137 vs. 103 minutes; P<0.0001 and 261 vs. 195 minutes; P<0.0001). There was no significant difference in inhospital mortality between the helicopter and ground transport groups (6.9% vs. 6.6%; P=0.88). Conclusions: Helicopter transport of STEMI patients was five times less effective than ground transport in maintaining the 90-minute first medical contact to primary percutaneous coronary intervention time recommended in guidelines, particularly for transfer distances less than 50 km.

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“…It is an observational prospective multicenter registry, which includes all patients undergoing coronary angiography or coronary angioplasty in each participant center. The methods used for this registry have been detailed previously 15,16 …”

Section: Methodsmentioning

confidence: 99%

“…The anonymous database includes up to 150 variables per procedure with hospital follow‐up data and at 1 year for any coronary angioplasty and pre‐hospital data for STEMI <24 h 15,16 . It includes demographic characteristics (age, sex, body mass index), risk factors (hypertension, diabetes mellitus, smoking, high cholesterol, family history of coronary heart disease, obesity), medical history and clinical presentation.…”

Section: Methodsmentioning

confidence: 99%

Is coronary multivessel disease in acute myocardial infarction patients still associated with worse clinical outcomes at 1‐year?

Puymirat

Nakache

Etienne

et al. 2021

Clinical Cardiology

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Background ST‐elevation myocardial infarction (STEMI) patients with multivessel disease (MVD) are associated with a worse prognosis. However, few comparisons are available according to coronary status in the era of modern reperfusion and optimized secondary prevention. Hypothesis We hypothesized that the difference in prognosis according to number of vessel disease in STEMI patients has reduced. Methods All consecutive STEMI patients undergoing primary percutaneous coronary intervention (PCI) within 24 h of symptoms onset between January 1, 2014 and June 30, 2016 enrolled in the CRAC (Club Régional des Angioplasticiens de la région Centre) France PCI registry were analyzed. Baseline characteristics, management, and outcomes at 1‐year were analyzed according to coronary status (one‐, two‐, and three‐VD). Results A total of 1886 patients (mean age 62.2 ± 14.0 year; 74% of male) were included. Patients with MVD (two or three‐VD) represented 53.7%. They were older with higher cardiovascular risk factor profile. At 1 year, the rate of major adverse cardiovascular events (MACE, defined as all‐cause death, stroke or re‐MI) was 10%, 12%, and 12% in one‐, two, and three‐VD respectively (p = .28). In multivariable adjusted Cox proportional hazard regression model, two‐ and three‐VD were not associated with higher rate of MACE compared to patients with single VD (HR, 1.09; 95%CI 0.76–1.56 for two‐VD; HR, 0.74; 95%CI 0.48–1.14 for three‐VD). Conclusions MVD still represents an important proportion of STEMI patients but their prognoses were not associated with worse clinical outcomes at 1‐year compared with one‐VD patients in a modern reperfusion area and secondary medication prevention.

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The CRAC cohort model: A computerized low cost registry of interventional cardiology with daily update and long-term follow-up

Cited by 22 publications

References 20 publications

Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry

Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry

Does helicopter transport delay prehospital transfer for STEMI patients in rural areas? Findings from the CRAC France PCI registry

Is coronary multivessel disease in acute myocardial infarction patients still associated with worse clinical outcomes at 1‐year?

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