The course and prognosis of ulcerative colitis: Part II Long-term prognosis

Epidemiology and Risk Factors for Hospitalization in Patients with Ulcerative Colitis and Crohn’s Disease

“…Early data regarding hospitalizations dates back to the 1930s. Edwards and Truelove prospectively followed a series of 624 patients from 1938 to 1962, and during this time, 38% required hospitalization [4]. Annual incidence rates of hospitalization in UC began to be more widely reported in the late 1960s and 1970s with rates ranging from 4.6 to 4.8 per 100,000 in Europe and the USA [5,6].…”

Resolved Hypereosinophilic Syndrome and Immune Thrombocytopenic Purpura in Ulcerative Colitis Patients Post Colectomy: A Case Series and Literature Review

“…In this article, we presented two cases of two comorbidities (HES and ITP) occurring in the context of chronic active UC and responding only to surgical colectomy. Though several cases of HES 18,[25][26][27][28] and ITP 14,23,[29][30][31][32][33][34][35][36][37][38][39] have been reported to co-occur with UC, the patients described in this article are unique in their presentation and treatment response. To the best of our knowledge, they represent rare cases of refractory comorbidities in the context of UC that failed conventional medical therapy and responded only to surgical treatment.…”

“…Concomitant occurrence of ITP and UC is rare. 14,23,[29][30][31][32][33][34][35][36][37][38][39] In patients with UC, ITP represents an extraintestinal manifestation of the disease mediated by immune-mediated mechanisms. 29 The differential diagnosis of thrombocytopenia is broad.…”