Currently, companies use for the diagnostic their performance different methods, parameters and indicators when the high current measurement and evaluation of effectiveness. Choosing the right key performance measures is to ensure the evaluation of the effectiveness with high recall and the possibility of subsequent infl uence and control very important. The main object of contribution is evaluating effi ciency in hospital facilities specialized for patients suffering from cardio-vascular diseases, ailments that affect the largest group of people in living in Slovakia. This followed the discovery that the number of newborns in Slovakia suffering from congenital heart diseases has increased over the recent years, and in the period between 2002 and 2012 annually 451 children at an average are born with this congenital disorder. Another factor that prompted our research was that the diseases of the circulatory system are rated among the most frequent cause of hospitalization and mortality in Slovakia, as confi rmed by the International Classifi cation of Diseases or the ICD (the international equivalent of the Slovak MKCH-10). Accordingly, people suffering from cardiovascular diseases belong to the most-frequently hospitalized patients. The third fi nding we have arrived at is the high level of consumption of prescription medicines by the Anatomical Therapeutic Chemical (ATC) Classifi cation, again dominated by cardio-vascular diseases. The paper describes both the cardio-vascular diseases and the hospital facilities specialized in their treatment, assessing their effi ciency in evaluating the major factors affecting them. The evaluation is carried out based on fi nancial ratios and application of prediction models. The ouptut of this contribution consists in the evaluation of the effi ciency of specialized hospital facilities (further only SHF) applying the DEA method and the evaluation of effi ciency of the SHFs using fi nancial ratios.