2013
DOI: 10.1016/j.jval.2012.11.011
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The Cost-Effectiveness of the Levonorgestrel-Releasing Intrauterine System for the Treatment of Idiopathic Heavy Menstrual Bleeding in the United States

Abstract: LNG-IUS resulted in the lowest treatment costs and the fewest number of hysterectomies performed over 5 years compared with all other initial strategies and resulted in the most quality-adjusted life-years gained among nonsurgical options. Initial treatment with LNG-IUS is the least costly and most effective option for women desiring to preserve their fertility.

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Cited by 15 publications
(12 citation statements)
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References 21 publications
(54 reference statements)
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“… 94 LNG-IUS 20 treatment resulted in the fewest hysterectomies and most quality-adjusted life-years, and it was less costly. 95 In another Cochrane Database Systematic Review , hysterectomy was found to reduce menstrual bleeding better than the LNG-IUS 20 at 1 year, but there was no evidence of a difference in patient satisfaction rates between surgery and LNG-IUS. 96 In that analysis, adverse events, such as bleeding and spotting, were more likely to occur with LNG-IUS, but surgery was more likely to cause serious complications.…”
Section: Iuds Currently Available In the Usmentioning
confidence: 96%
“… 94 LNG-IUS 20 treatment resulted in the fewest hysterectomies and most quality-adjusted life-years, and it was less costly. 95 In another Cochrane Database Systematic Review , hysterectomy was found to reduce menstrual bleeding better than the LNG-IUS 20 at 1 year, but there was no evidence of a difference in patient satisfaction rates between surgery and LNG-IUS. 96 In that analysis, adverse events, such as bleeding and spotting, were more likely to occur with LNG-IUS, but surgery was more likely to cause serious complications.…”
Section: Iuds Currently Available In the Usmentioning
confidence: 96%
“…In fact, the Mirena IUD is FDA approved for the management of menorrhagia. The LNG-IUD has been studied and found beneficial for women with chronic amenorrhea from other medical conditions as well as gynecologic disorders like menorrhagia and dysmenorrhea [47,48].…”
Section: Noncontraceptive Benefits Of Iudsmentioning
confidence: 99%
“…The authors recommended the use of the LNG-IUS for the management of such bleeding, over other effective treatments such as combined oral contraceptives, non-steroidal antiinflammatory drugs and luteal phase progestogens (Matteson et al 2013). In the US, it has been suggested that the LNG-IUS may be the most cost effective intervention for those who wish to preserve fertility (Ganz et al 2013).…”
Section: Reduced Bleedingmentioning
confidence: 99%