The Cortisone-Glucose Tolerance Test

The Influence of Age on the Renal Response to Water Deprivation in Man

“…Participants in the Longitudinal Study undergo a series of four tolerance tests of carbohydrate metabolism (oral glucose, cortisone glucose, intravenous glucose, intravenous tolbutamide) on successive visits. Performance on each test is converted to a percentile rank using nomograms developed from our study population [6][7][8], and categorized as previously described [8], The diagnosis of diabetes mellitus was made from a review of each subject's test results.…”

The oral glucose tolerance test: A study of the influence of age on the response to the standard oral 50 g glucose load

“…Conditions recommended for the conduct of the test [40] and criteria of normality for the different methods are now available [17]. These criteria, however, are open to criticism: distinction between normal subjects and chemical diabetics [38] remains arbitrary [8,9], and progressive reduction of carbohydrate tolerance with advancing age [1,2,3,4,7,10,11,14,17,20,21,22,23,25,37,39,43,44,45,46,47,49,50] is not taken into account. This reduction of carbohydrate tolerance with age appears to some authors to be so general, that they think it reasonable to make the criteria of normality age-dependent [4,7,22,37,49].…”

Diagnostische Kriterien des Frühdiabetes*

“…Das entspricht in etwa den Ergebnissen von Pozefsky (31), der eine Signifikanz ebenfalls erst nach 60 Minuten und einen progressiven Anstieg derselben vor allem im sechsten und in den folgenden Dezennien nachwies. Der durchschnittliche Blutzukkeranstieg lag bei seinen Versuchspersonen bei 17,6 mg/lOO ml für jedes Lebensjahrzehnt, unsere Progression ist wesentlich geringer.…”