Abstract:Asthma is an inflammatory disorder of the airways and inhaled corticosteroids are the most effective agents in controlling the disease process. The corticosteroid-dose response curve has traditionally been thought of as being flat, i.e. plateaus early, with no further therapeutic response with increasing dose of medication. This is only true for mild asthma and the improvement in airway calibre that occurs as inflammation subsides. For other parameters of asthma control, the dose-response curve is shifted to t… Show more
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