The correlations among racial/ethnic groups, hypertriglyceridemia, thrombosis, and mortality in hospitalized patients with COVID-19

Rodriguez, Maya; Dai, Wen; Lund, Hayley; Osinski, Kristen; Zhang, Ziyu; Silverstein, Roy L.; Zheng, Ze

doi:10.1016/j.beha.2022.101386

Cited by 3 publications

(1 citation statement)

References 52 publications

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“…121,[126][127][128] Development of hypertriglyceridemia is independently correlated with thrombosis incidence and inpatient mortality in those with severe COVID-19 infection, after adjusting for age, gender, and obesity. 129,130 Lp(a) is a risk factor for thrombotic cardiovascular disease, including myocardial infarction and ischemic stroke. [131][132][133][134] In patients with COVID-19, higher Lp(a) was reported to be positively associated with ischemic heart disease and venous thromboembolism.…”

Section: Hypercoagulability In Obesity and Dyslipidemiamentioning

confidence: 99%

Clot or Not? Reviewing the Reciprocal Regulation Between Lipids and Blood Clotting

Zhang,

Rodriguez,

Zheng

2024

ATVB

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Both hyperlipidemia and thrombosis contribute to the risks of atherosclerotic cardiovascular diseases, which are the leading cause of death and reduced quality of life in survivors worldwide. The accumulation of lipid-rich plaques on arterial walls eventually leads to the rupture or erosion of vulnerable lesions, triggering excessive blood clotting and leading to adverse thrombotic events. Lipoproteins are highly dynamic particles that circulate in blood, carry insoluble lipids, and are associated with proteins, many of which are involved in blood clotting. A growing body of evidence suggests a reciprocal regulatory relationship between blood clotting and lipid metabolism. In this review article, we summarize the observations that lipoproteins and lipids impact the hemostatic system, and the clotting-related proteins influence lipid metabolism. We also highlight the gaps that need to be filled in this area of research.

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Section: Hypercoagulability In Obesity and Dyslipidemiamentioning

confidence: 99%

Clot or Not? Reviewing the Reciprocal Regulation Between Lipids and Blood Clotting

Zhang,

Rodriguez,

Zheng

2024

ATVB

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Connecting impaired fibrinolysis and dyslipidemia

Rodriguez,

Zheng

2024

Research and Practice in Thrombosis and Haemostasis

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The use of selenium-containing drugs in the prevention and treatment of complications in patients with COVID-19

Dedov,

Poluboyarinov,

Fedorov

2023

Vrach

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Objective. To study literature data reflecting the use of selenium (Se) and selenium-containing drugs in the complex prophylaxis and treatment of complications in patients with COVID-19. Material and methods. Data analysis of 37 publications of scientists from Russian Federation, United States of America, People's Republic of China, Great Britain, India, France, Germany, Italy, Sweden, Canada, Brazil, United Arab Emirates, Saudi Arabia, Ireland, Holland, Greece, Australia, Poland, Pakistan, Sudan, Nepal was performed. The authors reflected on the epidemiology, diagnosis, pathogenesis, clinic, risk of acute respiratory distress syndrome, multiple organ failure, cardiovascular complications, mortality in patients with COVID-19, the importance of Se deficiency in the body and the preventive use of selenium-containing drugs in novel coronavirus infection. Results. Low dietary Se intake was associated with the development of acute respiratory distress syndrome in men and women with COVID-19. Deficiencies were associated with increased risk of morbidity and mortality. Organic forms of Se had the best bioavailability. Se had antioxidant, anti-inflammatory, antithrombotic, antiviral, immunomodulatory effects in patients with COVID-19. Conclusions. Thus, control and optimization of the selenium status in population of selenium-deficient areas with addition of Se-enriched food to the diet, as well as SELENBIO for women complex of Russian company "Parapharm" could be one of the directions of prevention and treatment of complications in patients with COVID-19.

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The correlations among racial/ethnic groups, hypertriglyceridemia, thrombosis, and mortality in hospitalized patients with COVID-19

Cited by 3 publications

References 52 publications

Clot or Not? Reviewing the Reciprocal Regulation Between Lipids and Blood Clotting

Clot or Not? Reviewing the Reciprocal Regulation Between Lipids and Blood Clotting

Connecting impaired fibrinolysis and dyslipidemia

The use of selenium-containing drugs in the prevention and treatment of complications in patients with COVID-19

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