The Correlation between Serum Selenium and Blood Selenium in Cattle

Maas, John; Galey, Francis D.; Peauroi, John R.; Case, James T.; Littlefield, Ethel S.; Koller, Loren D.; Crisman, Russel O.; Weber, D. W.; Warner, Dewey W.; Tracy, Mark

doi:10.1177/104063879200400111

Cited by 41 publications

(13 citation statements)

References 4 publications

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“…Homeostatic control mechanisms can limit changes in the serum concentrations of some trace minerals, notably Cu and Mn, until liver or other endogenous reserves are depleted Kincaid 1999;Hansen et al 2006). The measurement of Se in whole blood is preferred to serum by some investigators because serum selenium concentrations are more likely to be influenced by recent changes in the animal's intake than whole blood measurements (Maas et al 1992); however, agreement between serum and whole blood Se status was observed to be very good (a 00.79) at the herd level and good at the individual animal level (a00.68) for samples collected from beef cows in the fall of the year (Waldner et al 1998). …”

Section: Discussionmentioning

confidence: 99%

Serum micronutrient concentrations in beef cows before and after the summer grazing season

Weyer¹,

Hendrick²,

Waldner³

2010

Can. J. Anim. Sci.

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Van De Weyer, L. M., Hendrick, S. and Waldner, C. L. 2010. Serum micronutrient concentrations in beef cows before and after the summer grazing season. Can. J. Anim. Sci. 90: 563Á574. Serum concentrations of Cu, Mn, Mo, Se, vitamin A, and vitamin E were measured at the start and at the end of the summer grazing season in an observational field study of 791 commercial beef cows from 40 cow-calf herds from five community pastures. Copper and vitamin A were higher in the fall (PB0.001), and Mo (P B0.001) and selenium (PB0.001) were lower in the fall compared with the spring. Cows aged 10Á14 yr had lower concentrations of vitamin A (P B0.001) and vitamin E (spring: P00.010; fall: PB0.001) than cows aged 4Á9 yr. Cows with thin pre-breeding body condition scores were more likely to have lower pre-breeding Cu concentrations than cows that were not thin (P00.044). Cows that were thin at the end of the grazing season were more likely to have lower vitamin A concentrations at this time than cows that were not thin (P00.033). Trace mineral supplementation given before calving was associated with higher spring concentrations of Cu (P 00.007). Season of sample collection and the physiological status of the animals should be considered when interpreting the serum micronutrient status of beef cows and developing supplementation programs.

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Section: Discussionmentioning

confidence: 99%

Serum micronutrient concentrations in beef cows before and after the summer grazing season

Weyer¹,

Hendrick²,

Waldner³

2010

Can. J. Anim. Sci.

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“…Ulrey (1987) stated that the Se concentration in whole blood is between 10% and 50% higher than that in plasma. Maas et al (1992) reported blood Se to serum Se ratios of 2.41 ±0.81 (R 2 =0.77) and 2.25 ±1.12 (R 2 =0.82), depending on the analytical techniques used. These authors stated that these ratios are not constant over a range of blood Se concentrations.…”

Section: Ratio Between Selenium In Whole Blood and Plasmamentioning

confidence: 99%

“…In the early 1990s controversy was rife in the scientific literature between laboratories as to whether plasma/serum Se or whole blood Se was the preferred fluid to use in assessing the Se status of animals (Maas et al, 1992(Maas et al, , 1993Thompson and Ellison, 1993). For instance, Maas et al (1993) pointed out some limitations in using serum Se concentrations, viz.…”

Section: Introductionmentioning

confidence: 99%

Time-dependent effect of selenium supplementation on the relationship between selenium concentrations in whole blood and plasma of sheep

Ryssen

Coertze

Smith³

2013

Small Ruminant Research

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The ratio between selenium (Se) concentrations in pairs of plasma and whole blood of sheep after commencement of Se supplementation was calculated from data obtained from 10 independent investigations. The diets in the studies consisted of a variety of ingredients, from the individual feeding of feedlot diets to grazing trials on Se-deficient pastures. Means from 51 treatments, derived from 179 collections at various stages after commencement of Se supplementation, were used to calculate the ratios. In one study it was found that plasma Se concentration reached steady-state within 4 days of commencement, while Se in whole blood reached steady-state only at the collection 60 days after supplementation commenced. Using the 179 pairs, the ratio of whole blood and plasma stabilized at about 50 days after commencement when inorganic Se was supplemented, and at about 60-70 days when the Se was in the organic form. The ratios stabilized when they were between 2:1 and 3:1, and remained practically constant from 50 days post onset of supplementation, when plasma Se constituted 0.445 of whole blood Se concentration for the inorganic Se source and 0.410 when the Se source was organic. It was concluded that after commencement of Se intake, plasma Se concentration remains relatively constant from within 4 days of onset, while whole blood Se concentration apparently reaches steady-state only after approximately 50 days. Before 50 days, whole blood Se seems not to be reliable to predict the Se status of an animal. In a situation where Se intake is stable and Se requirements do not fluctuate, a bloodplasma ratio of between 2:1 and 3:1 would be a guideline to indicate that whole blood Se and plasma Se concentrations could both be used to assess the Se status of sheep.

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“…The use of serum Se concentration to assess nutritional status of cattle with respect to selenium was shown not to be appropriate [8]. Despite variability in renal free water clearance, the urinary selenium concentration appears to be a sensitive indicator of sodium selenite consumption in excess of nutritional requirements in cows [3].…”

Section: Introductionmentioning

confidence: 99%

The urinary excretion of selenium in sheep treated with a vasopressin analogue

et al. 2000

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-The renal excretion of selenium was investigated in ewes with an excretion of hypotonic urine (control group) and in ewes with a formation of highly concentrated urine. Chronic stimulation of the urinary concentrating activity of sheep kidneys was induced by a long-term treatment with 1-desamino-8-D-arginine vasopressin (dDAVP), a synthetic analogue of vasopressin with prolonged effects. Young animals with 22 to 25 kg b.w. were fed a normal protein diet providing a daily intake of 129.25 g of crude protein, 12.03 MJ of digestible energy and 0.18 mg of selenium for 3 weeks. The vasopressin treated sheep (n = 11) were given subcutaneous injections of 12.5 µg of dDAVP in glycerol twice daily for one week before the clearance measurement of renal functions. The control group (n = 11) was treated with glycerol only. The administration of dDAVP resulted in a highly significant decrease of the urinary flow rate (from 3.19 ± 0.50 in control group to 0.33 ± 0.03 mL·min -1 in dDAVP animals, P < 0.001) without changes in the glomerular filtration rate (80.18 ± 6.36 in controls vs. 77.86 ± 6.26 mL·min -1 , NS). No effects on plasma selenium level were observed (0.17 ± 0.03 in controls vs. 0.20 ± 0.03 µmol·L -1 , NS) but the amounts of selenium excreted were found to be highly significantly reduced (from 0.29 ± 0.05 in controls to 0.03 ± 0.01 nmol·min -1 , P < 0.001) in dDAVP treated sheep. Despite a large reduction in urinary flow rate, the selenium concentration in urine was actually the same in both groups (0.09 ± 0.01 µmol·L -1 ) resulting in a sharp fall in the renal clearance of selenium (2.20 ± 0.54 in controls vs. 0.18 ± 0.03 mL·min -1 , P < 0.01) due to dDAVP. This seems to be a consequence of the large increase in the selenium solvent drag induced by a vasopressin treatment. The results presented suggest that vasopressin may contribute to maintenance of the selenium balance in sheep via its effects on renal function.sheep / kidney / renal function / vasopressin / selenium excretion Vet. Res. 31 (2000)

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The Correlation between Serum Selenium and Blood Selenium in Cattle

Cited by 41 publications

References 4 publications

Serum micronutrient concentrations in beef cows before and after the summer grazing season

Serum micronutrient concentrations in beef cows before and after the summer grazing season

Time-dependent effect of selenium supplementation on the relationship between selenium concentrations in whole blood and plasma of sheep

The urinary excretion of selenium in sheep treated with a vasopressin analogue

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