The correlation between serum leptin and blood pressure after exposure to noise at work

Abstract

Several epidemiologic studies have reported that exposure to noise is associated with cardiovascular disease. The increased body weight is often associated with metabolic as well as increased blood pressure. The aim of this study is to investigate the correlation between the elevation of blood pressure and serum leptin hormones due to the effects of noise in the work place. A total of 80 volunteer males where included in this study with an age range between of 20 and 45 years, they were divided in two groups equally, the 1 st group were exposed to noise in the workplace while the 2 nd group were not. The individual noise exposure was determined by using a sound level meter. The range of noise was 80-100 dBA. Body Mass Index was also taken for each individual by a standard measure, blood pressure was measured by OMRON sphygmomanometer and serum leptin was measured through venous blood sample analysis enzyme linked immunosorbent assay. Spearman rank order correlation was used to examine the correlations between Blood pressure value (Systolic, Diastolic) and Leptin. All the relationships between parameters showed a positive correlation. Systolic and diastolic blood pressure values had a significant correlation to leptin hormone level in comparison to the control. There was a significant relation between leptin and blood pressure. leptin effects on the sympathetic nervous system may provide a partial explanation. Therefore, Leptin might have diverse cardiovascular actions.

ICBEN review of research on the biological effects of noise 2011-2014

“…For this review, the literature published during the period from August 2011 to December 2013 was searched. Sixty peer-reviewed journal publications were identified,[ 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 ] which indicated that an impressive amount of progress in the field was made during the last 3 years. Many results were published based on data analyses of existing or ongoing cohort studies.…”

“…To investigate the physiological mechanism through which noise exposure may lead to CVD and hypertension, laboratory studies[ 111 112 ] and field studies[ 84 113 114 115 116 117 ] were carried out, with a variety of outcomes. Three studies[ 111 112 113 ] focused on noise and vibration during nighttime.…”

“…Three studies[ 111 112 113 ] focused on noise and vibration during nighttime. One study[ 114 ] was carried out for 24 h. Other studies[ 84 115 116 117 ] investigated the effects of daytime noise. There is sufficient evidence for a relationship between insufficient sleep and changes in metabolic and endocrine functions, which in the long term may lead to CVD and hypertension.…”

A vision of the environmental and occupational noise pollution in Malaysia

“…An explicit link between environmental noise with the activation of sympathetic and endocrine systems has been witnessed, resulting in the changes of blood pressure, hypertension, peripheral vasoconstriction and cardiovascular disease. [6] Scientific evidence [7] has proposed that chronic aircraft noise exposure may impair reading comprehension and long-term memory among children whereas high noise level of industrial settings is subjected to nausea, headaches, argumentativeness and modulation of mood and anxiety [ Figure 2]. Epidemiological studies have shown that irregular traffic noise of 45 dBA has been interlinked to the interference of daily activities, sleeping, rest, study, communicating, and adverse health implications such as frustration, lower tolerance, and changes of blood compositions.…”

The Effects of Traffic Noise on Serum Levels of LDH in Male Rats

“…These annoyance reactions are associated with the degree of magnitude, variety, and severity on the daily activities [9]. The health impacts of noise pollution and the potential implications of noise exposure are numerous, pervasive, persistent, cumulative and augmented synergistically and antagonistically, with corresponding real (economic) and intangible (well-being) losses [10]. An explicit link between environmental noise with the activation of sympathetic and endocrine systems has been witnessed, resulting in the changes of blood pressure, hypertension, peripheral vasoconstriction and cardiovascular disease [11].…”