The correlation between dietary fat quality indices and lipid profile with Atherogenic Index of Plasma in obese and non-obese Volunteers: a cross-sectional descriptive-analytic case-control study

Abstract

Background and aim: Abnormalities in lipid metabolism are commonly observed in patients who were obese. Alongside dyslipidemia, one of the markers in predicting the risk of cardiovascular disease is the Atherogenic Index of Plasma (AIP), which is related to dietary intake. Healthy fat quality indices might affect on AIP. The purpose of this study is to find the possible relationship between dietary fat quality, and AIP and comparison of these indices among obese and non-obese volunteers.Methods: This study was a cross-sectional descriptive-analytic case-control study with 157 normal and overweight and obese volunteers (n=71 normal, Age: 38.90±10.976 vs n=86 overweight/obese, Age: 38.60±9.394) in the age range of 18-65 years. Food intake was measured using FFQ, anthropometric indices (weight, height, body mass index and waist to hip ratio), body composition (visceral fat level, total body water, body fat mass), and lipid profile were measured. Results: Based on the present results, comparable biochemical parameters including TC (P=0.580), TG (P=0.362), LDL (P=0.687) and HDL (P=0.151) among overweight/obese volunteers as compared to normal ones were noticed. Effects of dietary fat quality, including Atherogenicity (AI) and Thrombogenicity (TI) hypo/hypercholesterolemic ratio (h/H), the Cholesterol-Saturated Fat Index (CSI) showed significantly higher AI (P=0.012) in the overweight/obese group as compared to the normal group. Whereas, h/H (P=0.034) and ω-6/ω-3 ratio (P=0.004) were significantly higher in normal-weight volunteers. There was a positive correlation between AI, TI, CSI, SFA, MUFA, PUFA and ω-6/ω-3 ratio with AIP and negative correlation between h/H with AIP in both groups. Despite the significances of these correlations no strong relation was observed by doing multiple regression among normal and overweight/obese groups (R2=0.210, R2=0.387).Conclusions: In summary, the present work proposes a direct relationship between dietary fat quality, increased BMI, and lipid abnormalities with AIP. Nevertheless, further large-scale studies are required to sustain a clear conclusion in this wish.

Bocaiuva (Acrocomia aculeata) nut oil: composition and metabolic impact in an experimental study

“…The AI and TI are important tools to verify the nutritional quality of dietary fat because the lower the values of these indexes, the greater the amount of anti-atherogenic fatty acids present in a given oil/fat and, consequently, the greater the potential for preventing the onset of cardiovascular diseases (Javardi et al, 2020).…”

In Vitro Antioxidant Activities of Plant Polyphenol Extracts and Their Combined Effect with Flaxseed on Raw and Cooked Breast Muscle Fatty Acid Content, Lipid Health Indices and Oxidative Stability in Slow-Growing Sasso Chickens

“…The current AI and TI values in both raw and cooked breast muscle were less than 1, which is in the recommended range to provide health benefits [99]. According to [97], diets with a higher TI promote the formation of clots in blood vessels. A decrease in TI values in foods is associated with lower health risks [99,100].…”

“…Similarly, the thrombogenic indices (TI) of breast meat (both raw and cooked) of chickens fed with plant extract containing diets and FS were not significantly different (p > 0.05). The AI, TI, and h/H ratio are health and nutritional value indicators of lipids [97]. The AI is a major indicator of cardiovascular risk [98], and its lower value suggests that consumption of such meat could potentially contribute to a decrease in cardiovascular risk.…”

Hubungan Antara Parameter Antropometri Dan Profil Lipid Pada Wanita Sehat Di Semarang

“…Beberapa penelitian sebelumnya menunjukkan hasil yang sama. [33][34][35] Obesitas, berdasarkan IMT, berhubungan dengan gangguan profil lipid. 6,9 Indeks massa tubuh yang merupakan parameter untuk menentukan status gizi pada dewasa untuk memprediksi beberapa profil lipid.…”