The correlation between anxiety, depression, and vertigo: a cross-sectional study

Abstract

Background Dizziness, including vertigo, affects approximately 15% to over 20% of adults each year. A significant proportion of patients with vertigo develop secondary psychiatric disorders throughout their disease. On the other hand, patients with psychiatric disorders frequently report dizziness as a co-occurring symptom of their illness. The purpose of this study was to screen the prevalence of depression and anxiety indices in dizzy patients and their relation to the severity of their dizziness handicap by administering two different questionnaires: The dizziness handicap inventory (DHI) and the Hospital Anxiety and Depression Scale (HADS). Results Psychological assessments revealed that 49% of the study group was normal, 29% had anxiety, 7% had depression, and 15% had both anxiety and depression. Besides, vestibular neuritis was associated with a higher mean anxiety score, whereas Meniere's disease was associated with a higher mean depression score. Conclusion As this study has shown, there was a statistically significant positive correlation between anxiety and depression scores and physical, emotional, functional, and total DHI scores. Screening and treatment of co-morbid mental health disorders are critical for appropriate management of vertigo disability that leads to a higher quality of life and fewer complications.

Both systemic Calcitonin Gene Related Peptide (CGRP) and a vestibular challenge promote anxiety-related behaviors and dynamic imbalance in mice

“…We also observed reduced movement in the EPM when we measured a mouse's bouts through the center, as mice treated with OVAR were not as active as their pre-OVAR state after IP vehicle or IP CGRP injections. This motion-induced anxiety and reduced activity observed during EPM is of clinical importance, as a clear, positive correlation between anxiety, depression, and vertigo is observed in patients with vestibular disorders (Omara et al 2022), and so studying this link in mouse models provides insight into this correlation. The EPM is also a suitable assay as a surrogate behavior for agoraphobia in was not certified by peer review) is the author/funder.…”

A Vestibular Challenge Combined with Calcitonin Gene-Related Peptide (CGRP) Promotes Anxiety-Like Behaviors

“…However, while mice were less active after OVAR, they only exhibited increased anxiety after CGRP infusion with OVAR. This motion-induced anxiety and reduced activity observed during EPM is of clinical importance, as a clear, positive correlation between anxiety, depression, and vertigo is observed in patients with vestibular disorders ( Omara et al, 2022 ), and so studying this link in mouse models provides insight into this correlation. The EPM is also a suitable assay as a surrogate behavior for agoraphobia in mouse models for migraine, as mice spend more time in the closed arms when they exhibit anxiety-like behaviors, and mirrors patients’ tendencies to avoid open spaces during VM attacks ( Kutay et al, 2017 ).…”

Effectiveness of Telerehabilitation in Dizziness: A Systematic Review with Meta-Analysis

“…Whilst DHI explores each of the three ICF domains (activity, participation, body function and structures), VSS-SF focuses only on "body functions and structures" [54]. The remaining HADS, PHQ-9, GAD-7 and BDI-II have been frequently utilized in clinical vestibular research [24,55,56], considering the emotional, cognitive and psychological impacts of dizziness [57,58], which can result in a deterioration of the quality of life [59][60][61].…”

“…Dizziness is a highly debilitating symptom. Individuals who suffer from it may experience a reduction in quality of life [59][60][61] and sleep, cognitive impairments, fear of movement, and increased risk of developing anxiety, depression, and panic attacks [57][58][59]86]. Physiotherapeutic intervention is safe, effective, and free from serious adverse effects, reduces the need for medication, and reduces the occurrence of dizziness in the medium to long term [21].…”