The corrected nucleotide séquence of valine tRNA from baker's yeast

Bonnet, Jacques; Ebel, Jean Pierre; Dirheimer, G.; Shershneva, L.P.; Krutlina, A.I.; Venkstern, T. V.; Bayev, A.A.

doi:10.1016/s0300-9084(74)80013-1

Cited by 34 publications

(9 citation statements)

References 8 publications

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“…The tRNA yr gene, SUP2, described here is allelic to the gene associated with a sigma sequence which was previously analyzed (6). The sigma element in lambda 43 is adjacent to sequence which is homologous, at least as far as the T loop, to the tRNAValsequence reported from yeast by Bonnet et al (47). This gene is not allelic to the tRNAVl gene described by Baker et al (44).…”

Section: Genementioning

confidence: 79%

Sigma elements are position-specific for many different yeast tRNA genes

Sandmeyer

Bilanchone²,

Clark³

et al. 1988

Nucl Acids Res

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We determined the DNA sequence of seventeen sigma elements and flanking regions in order to investigate the extent of the association between the yeast repetitive element, sigma, and tRNA genes. Fifteen of seventeen sigma elements analyzed begin at position -19 to -16 with respect to the 5' end of a tRNA-coding sequence. This region is close to the initiation point of tRNA gene transcription and contains a sequence which is modestly conserved for a number of tRNA genes. Two pairs of identical sigma elements occur as the long terminal repeats of a sequence which, together with flanking sigma elements, has the structural properties of a retrotransposon; this element has been named Ty3 (manuscript submitted). Hybridization analysis of yeast chromosomal DNA separated by orthogonal field alternation gel electrophoresis (OFAGE) showed that Ty3 and isolated sigma elements are distributed over many chromosomes in the yeast genome.

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Section: Genementioning

confidence: 79%

Sigma elements are position-specific for many different yeast tRNA genes

Sandmeyer

Bilanchone²,

Clark³

et al. 1988

Nucl Acids Res

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“…(C) 3-D wire model of the tRNA-like structure (86 nucleotides) as proposed in (10). (D) Secondary structure of yeast tRNA Val(12). (E) Scheme of the folding of yeast tRNA Val (to be compared with (B)).…”

mentioning

confidence: 99%

3-D Graphics Modelling of the tRNA-Like 3′-End of Turnip Yellow Mosaic Virus RNA: Structural and Functional Implications

Dumas

Moras

Florentz

et al. 1987

Journal of Biomolecular Structure and Dynamics

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The tRNA-like structure of the aminoacylatable 3'-end of turnip yellow mosaic virus (TYMV) RNA was submitted to 3-D graphics modelling. A model of this structure has been inferred previously from both biochemical results and sequence comparisons which presents a new RNA folding feature, the "pseudoknot". It has been verified that this structure can be constructed without compromising accepted RNA stereochemical rules, namely base stacking and preferential 3'-endo sugar pucker. The model has aided interpretation of previous structural mapping experiments using chemical and enzymatic probes, and new accessibilities of residues could be predicted and tested. Pseudoknots have been considered as potential splice sites because they form antiparallel helical segments in a single RNA molecule. We have examined this possibility with the constructed 3-D model and could verify the hypothesis on a structural basis. The model presents a striking similarity with canonical tRNA and allows a valuable comparison between the protection patterns of yeast tRNA(Val) and tRNA-like viral RNA by cognate yeast valyl-tRNA synthetase against structural probes.

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“…The tRNAlike structure is entirely encompassed within the 3' non-coding end of the viral RNA, it is devoid of modified bases (13,14) and interestingly, CAC a valine anticodon, can be adequately positioned in a possible "anticodon" loop. However, the viral tRNA-like structure bears little resemblance to the classical secondary structure of a tRNA and contains but few sequence similarities with valine tRNAs (16)(17)(18). It has recently been reported (19) that more than 56% sequence homology exists between the 3'-terminal 80 nucleotides of TYMV RNA and the corresponding region in the RNA of the Cowpea strain of tobacco mosaic virus (TMV), a member of the tobamovirus group whose RNA accepts valine instead of histidine (20).…”

mentioning

confidence: 99%

Length requirements for tRNA-specific enzymes and cleavage specificity at the 3′ end of turnip yellow mosaic virus RNA

1982

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This paper describes the minimum length of the turnip yellow mosaic virus (TYMV) RNA necessary to fulfill the tRNA-like properties of the viral RNA: 50 to 75 nucleotides and 86 nucleotides from the 3' end of TYMV RNA are sufficient for adenylation and valylation respectively by the Escherichia coli system. The size of the tRNA-like fragments obtained in vitro in the presence of an E. coli, a reticulocyte or a chinese cabbage leaf extract has also been determined. Among the major fragments liberated from the 3' end of TYMV RNA by the three systems are fragments of 117 and 112 nucleotides. In addition, the E. coli extract liberates fragments of 139 and 61 nucleotides, and the reticulocyte lysate fragments of 109, 94, 84, 73 and 46 nucleotides. The cleavage of the viral RNA by several systems in vitro to yield RNA fragments encompassing the tRNA-like sequence suggests that such fragments might also be liberated in vivo.

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The corrected nucleotide séquence of valine tRNA from baker's yeast

Cited by 34 publications

References 8 publications

Sigma elements are position-specific for many different yeast tRNA genes

Sigma elements are position-specific for many different yeast tRNA genes

3-D Graphics Modelling of the tRNA-Like 3′-End of Turnip Yellow Mosaic Virus RNA: Structural and Functional Implications

Length requirements for tRNA-specific enzymes and cleavage specificity at the 3′ end of turnip yellow mosaic virus RNA

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