2021
DOI: 10.1097/mrm.0000000000000267
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The coronavirus disease 2019 and effect on liver function: a hidden and vital interaction beyond the respiratory system

Abstract: Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) emerged in December 2019 in Wuhan province, China. SARS-CoV-2 causes coronavirus disease 2019 . Angiotensin-converting enzyme 2 (ACE2) has an essential role as a receptor in the entry of the SARS-CoV-2 into the host cells. It has been declared, ACE2 expresses in the lungs, heart, kidneys, placenta, and liver. This study reviews the liver's markers' characteristics in patients with COVID-19 to achieve novel insights in improving clinical treat… Show more

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Cited by 18 publications
(19 citation statements)
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References 217 publications
(298 reference statements)
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“…Second, we tend to calculate the pooled prevalence based on WHO territorial office data and perform spatial analysis in several geographical districts to distinguish the high-risk area for viral coinfection [68][69][70][71][72][73][74][75][76], but this estimation may be unreliable because of the small number of studies.…”
Section: Discussionmentioning
confidence: 99%
“…Second, we tend to calculate the pooled prevalence based on WHO territorial office data and perform spatial analysis in several geographical districts to distinguish the high-risk area for viral coinfection [68][69][70][71][72][73][74][75][76], but this estimation may be unreliable because of the small number of studies.…”
Section: Discussionmentioning
confidence: 99%
“…With this in mind, both SARS-CoV and SARS-CoV-2 exploit angiotensin-converting enzyme 2 (ACE-2) receptor, while MERS-CoV employs dipeptidyl peptidase 4 (DPP4, also known as CD26) (5)(6)(7). The binding of the spike glycoproteins of SARS-CoV-2 (2SP) to ACE-2 enables the process of cell entry (8,9).…”
Section: Contextmentioning
confidence: 99%
“… 3 Mass testing against SARS‐CoV‐2 and in some circumstances alone with other bacterial, viral, or fungal microbiota is also encouraged for a wide range of COVID‐19 control measures, such as screening for community transmission 4 and evaluation for disease progression of COVID‐19 patients with/without coinfection of other microbial agents. 5 , 6 , 7 , 8 …”
Section: Introductionmentioning
confidence: 99%
“…3 Mass testing against SARS-CoV-2 and in some circumstances alone with other bacterial, viral, or fungal microbiota is also encouraged for a wide range of COVID-19 control measures, such as screening for community transmission 4 and evaluation for disease progression of COVID-19 patients with/without coinfection of other microbial agents. [5][6][7][8] Pooling of clinical specimens for mass detection of SARS-CoV-2 by nucleic acid testing has been reported to be effective in increasing diagnostic capacity with sufficient accuracy [9][10][11] for prompt disease intervention, especially when the prevalence of infected cases is low. In Taiwan, routine diagnosis of COVID-19 among individuals with suspected disease is conducted through a comprehensive nationwide SARS-CoV-2 laboratory network that comprises a total of 245 clinical laboratories at regional hospitals and medical institutions with a maximum daily capacity of 149,660 tests as of September 27, 2021.…”
mentioning
confidence: 99%