The conversion factor for predicting adenoma detection rate from polyp detection rate varies according to colonoscopy indication and patient sex

Abstract

The adenoma detection rate (ADR) is the primary quality indicator for colonoscopies. The polyp detection rate (PDR) is available from administrative data and does not depend on histology verification. The correlation between PDR and ADR and the ADR/PDR conversion factor in preventive colonoscopies were evaluated. In the prospective study, asymptomatic individuals aged 45–75 years with preventive colonoscopy in 2012–2016 were included. Spearman’s correlation coefficient was used to assess PDR/ADR for each endoscopist. Conversion factor predicting ADR from PDR was obtained by linear regression and subsequently compared with adenoma to polyp detection rate quotient. One thousand six hundred fourteen preventive colonoscopies performed by 16 endoscopists in 8 screening colonoscopy centres in the Czech Republic were analysed. Correlation between PDR and ADR in all preventive colonoscopies was high and statistically significant (Rs 0.82; P < 0.001). There was a strong correlation between PDR and ADR in men (Rs 0.74; P = 0.002) and in screening colonoscopies (Rs 0.85; P < 0.001). The conversion factor to convert ADR from PDR was 0.72 in all preventive colonoscopies, 0.76 in FOBT+ colonoscopies and 0.67 in screening colonoscopies. ADR may be replaced by PDR in the assessment of colonoscopy quality. The value of the conversion factor varies according to colonoscopy indication and gender of examined individuals; in this Czech study, it was 0.72 in all preventive colonoscopies. The minimum requested ADR of 25 % corresponds to a PDR of 35 %, when converted with the appropriate conversion factor.

Adenoma Detection Rate in Average-Risk Population: An Observational Consecutive Retrospective Study

“…Although previous studies 16 , 17 have confirmed that postmenopausal estrogen and progesterone replacement therapy can reduce the risk of CRC, whether menopause increases the incidence of colorectal adenomas remains unclear. Although many previous studies have confirmed that the male sex is associated with higher ADR, 18 - 20 to the best of our knowledge, our study is the first to find that ADR increases markedly at an earlier age of approximately 5 years in average-risk of men compared to women. We also found the same trend in AADR, although it was not statistically significant.…”

Comparison of Four Bowel Cleansing Agents for Colonoscopy and the Factors Affecting their Efficacy. A Prospective, Randomized Study

“…Moreover, two other performance measures for colonoscopy, cecal intubation rate (CIR) and the adenoma detection rate (ADR), depend on the quality of bowel preparation [5]. Using an appropriate conversion factor, polyp detection rates (PDRs) can replace ADRs for colonoscopy quality assessments [6]. Based on quality indicators, the European Society of Gastrointestinal J Gastrointestin Liver Dis, June 2021 Vol.…”