The control of reproduction in finfish species through GnRH treatments

Rainis, Simona; Ballestrazzi, Rodolfo

doi:10.4081/ijas.2005.345

Cited by 8 publications

(5 citation statements)

References 18 publications

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“…During farming procedures, environmental parameters of rearing, diet, genetics or gonadotropin‐releasing hormone GnRH treatments can affect and modify the fish reproductive cycle. Laboratory‐synthesized GnRH and analogues are frequently used in farms, although natural GnRH extracted from the hypothalamus is more efficient, cheaper and easily available on the market to overcome the technological and biological limits of “traditional” hormonal treatments with human chorionic gonadotropin (hCG) ((Rainis & Ballestrazzi, 2005)). It is well known that with regard to male fish, substances such as pituitary gland extracts and hCG have been used to improve gonadal maturation and induce spermiation, injected alone or mixed together.…”

Section: Discussionmentioning

confidence: 99%

Testicular leiomyoma and spermatogenic failure syndrome in a seabass from broodstock

Natale

Capparucci

Abbate

et al. 2020

Journal of Fish Diseases

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Testicular leiomyomas and gonadal dysfunctions are not commonly reported in teleost and particularly in broodstock fish. In the present work, a testicular leiomyoma related to an unusual case of spermatogenic failure syndrome, in a broodstock seabass coming from an Italian aquaculture farm, is reported. At gross pathology, the circumscribed neoplasia showed several white nodular masses, originating from the gonad, deforming the anatomo‐physiological shape. From light microscopy, the presence of neoplastic tissue islands with spindle cells with a whirling pattern and the low presence of connective tissue were evident and originated from smooth muscle cells. Seminiferous tubules showed severe azoospermia with the absence of sperm cells even closer to the neoplastic area. Immunohistochemical analysis was positive for alpha‐SMA, desmin and vimentin but negative for S‐100, confirming a diagnosis of leiomyoma. This is the first report of spermatogenic failure syndrome associated with a testicular leiomyoma in fish from broodstock. More efforts should be made in studying broodstock fish pathologies related to fish maintenance and hormonal treatments that could economically affect aquaculture production.

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Section: Discussionmentioning

confidence: 99%

Testicular leiomyoma and spermatogenic failure syndrome in a seabass from broodstock

Natale

Capparucci

Abbate

et al. 2020

Journal of Fish Diseases

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“…Decapeptide GnRH analogues commonly used in finfish breeding are an analogue of mammalian GnRH, called LHRHa and an analogue of salmon GnRH, called sGnRHa [7,102]. GnRH analogues are primarily designed from the functional decapeptide region.…”

Section: Gnrh Analogues In Induced Breedingmentioning

confidence: 99%

“…Fish maintained in different aquaculture system fail to experience natural environmental conditions, and result in the failure of reproductive system to complete normal gametogenic cycle in the captivity. Cultured adult fish exhibit different form of reproductive dysfunction, observed during seasonal reproductive cycle [1][2][3][4][5][6][7][8][9]. In gonochortistic female teleost fish, the two major problems encountered are failure to initiate and complete the vitellogenesis, and the other is failure to undergo final oocyte maturation and ovulation, after completion of vitellogenesis in the captivity.…”

Section: Introductionmentioning

confidence: 99%

A Review on the Reproductive Dysfunction in Farmed Finfish

Sethu

Chidambaram

Ezhilarasi

et al. 2021

ARRB

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Globally, fish production in the wild is decreasing, and different aquaculture systems are presently being used for broodstock development in the captivity. Seasonally, broodstock raised in captivity exhibit different form of reproductive dysfunction at the level of the brain-pituitary-gonad (BPG) axis. Primarily, vitellogenic completion and final oocyte maturation are inhibited in females, and males fail to spermiate spontaneously in the captivity. Reproductive dysfunctions are also observed during sexual differentiation, pubertal onset and sex conversion periods in teleosts. To overcome these problems, different hormonal preparations, primarily gonadotropin-releasing hormones (GnRH) are used. In recent years, kisspeptins have been shown to be potent in inducing gonadal growth and maturation in teleost fish. Understanding the form of reproductive dysfunction is important in formulating suitable hormonal preparations for inducing gametogenesis. The paper reviews the problem of reproductive dysfunction and their possible reason for formulating different hormonal preparations.

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“…(Blázquez et al, 1998, Dufour et al, 2010. The hypothalamus also produces dopamine, which, on the contrary, shows inhibitory effects on the HPG axis (Rainis and Ballestrazzi, 2005, Zohar et al, 2010). At the brain level, GnRH and also GRIF (gonadotropin release-inhibiting factor, reported in few teleost) secreting neurons originate in the preoptic area (nucleus preopticus, NPO) of the hypothalamus and innervate the pituitary gland (Peter and Paulencu,…”

mentioning

confidence: 99%

Multifactorial control of gonadotropin release for induction of oocyte maturation: Influence of gonadotropin-releasing hormone, gonadotropin release-inhibiting factor and dopamine receptors in the catfish, Heteropneustes fossilis

Kumari

Sehgal

Goswami

et al. 2021

JANS

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Several external and internal factors contribute to the reproductive success of teleosts, which makes the reproductive process complex and unique. In the Indian freshwater catfish, Heteropneustes fossilis, monsoon plays a crucial role as it fine tunes the neuroendocrine axis, culminating in oocyte maturation. Therefore, induction of oocyte maturation requires the coordinated interaction among hypothalamic, hypophyseal, and peripheral hormones. In the present investigation, dual neuroendocrine control of oocyte maturation has been demonstrated in the catfish, H. fossilis. The maturational response in gravid catfish is inhibited in the presence of dopamine but GnRH evokes the oocyte maturation and ovulation. GnRH upregulates the expression of lhb gene as well as increases plasma levels of LH significantly within 30 minutes of its administration. Destruction of the preoptic region in gravid catfish by electrolytic or chemical lesions also causes oocyte maturation and ovulation. But this response is inhibited if dopamine is injected into the nucleus preopticus periventricularis-lesioned fishes. These observations support the role of dopamine as an inhibitory factor, therefore specific receptors of dopamine have been characterized in catfish and their expression in the brain has been quantified. Dopamine receptors are upregulated in dopamine-treated fishes and downregulated if a dopamine antagonist (pimozide) is injected. The present study suggests the presence of inhibitory mechanism for LH secretion in gravid catfish. Abolition of this inhibition is necessary to release LH surge, which in turn stimulates resumption of meiosis and ovulation. Thus peptidergic as well as aminergic systems regulate oocyte maturation in H. fossilis. Neuroendocrine regulation of oocyte maturation and ovulation has major implications for inducing spawning in aquaculture.

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The control of reproduction in finfish species through GnRH treatments

Abstract:
Fish in captivity can show some dysfunctions, at different levels, in the physiological processes of reproduction, due to

the lack of synthesis or release of gonadotropins (GtHs) by hypophysis. As a consequence, a worsening of quality and

Show more

Cited by 8 publications

References 18 publications

Testicular leiomyoma and spermatogenic failure syndrome in a seabass from broodstock

Testicular leiomyoma and spermatogenic failure syndrome in a seabass from broodstock

A Review on the Reproductive Dysfunction in Farmed Finfish

Multifactorial control of gonadotropin release for induction of oocyte maturation: Influence of gonadotropin-releasing hormone, gonadotropin release-inhibiting factor and dopamine receptors in the catfish, Heteropneustes fossilis

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The control of reproduction in finfish species through GnRH treatments

Abstract: Fish in captivity can show some dysfunctions, at different levels, in the physiological processes of reproduction, due to the lack of synthesis or release of gonadotropins (GtHs) by hypophysis. As a consequence, a worsening of quality and Show more

Cited by 8 publications

References 18 publications

Testicular leiomyoma and spermatogenic failure syndrome in a seabass from broodstock

Testicular leiomyoma and spermatogenic failure syndrome in a seabass from broodstock

A Review on the Reproductive Dysfunction in Farmed Finfish

Multifactorial control of gonadotropin release for induction of oocyte maturation: Influence of gonadotropin-releasing hormone, gonadotropin release-inhibiting factor and dopamine receptors in the catfish, Heteropneustes fossilis

Contact Info

Product

Resources

About

Abstract:
Fish in captivity can show some dysfunctions, at different levels, in the physiological processes of reproduction, due to

the lack of synthesis or release of gonadotropins (GtHs) by hypophysis. As a consequence, a worsening of quality and

Show more