The control of pain due to dentin hypersensitivity in individuals with molar–incisor hypomineralisation: a protocol for a randomised controlled clinical trial

Sobral, Ana Paula Taboada; Santos, Elaine Marcílio; Aranha, Ana Cecília; Soares, Paulo Vinícius; Moriyama, Caroline Moraes; Gonçalves, Marcela Letícia Leal; Ribeiro, Rodrigo Alves; Motta, Lara Jansiski; Horliana, Anna Carolina Ratto Tempestini; Fernandes, Kristianne Porta Santos; Mesquita‐Ferrari, Raquel Agnelli; Bussadori, Sandra Kalil

doi:10.1136/bmjopen-2020-044653

Cited by 5 publications

(2 citation statements)

References 13 publications

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“…Such sensitivity can be triggered by toothbrushing, consuming hot and/or cold drinks, and consuming acidic foods. This situation causes pain, restlessness, and a decrease in the quality of life of the affected individuals [82][83][84][85]. In the literature, the number of studies on the elimination of hypersensitivity in anterior teeth affected by MIH is very low.…”

Section: Approaches To Relieving Hypersensitivitymentioning

confidence: 99%

Treatment Strategies for Incisors of Children Affected by Molar Incisor Hypomineralization: A Narrative Review

Sezer,

Çarıkçıoğlu

2024

Oral

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Today, molar incisor hypomineralization (MIH), which affects approximately one in seven children, is defined as a hypomineralized developmental enamel defect that often impacts at least one permanent first molar and frequently affects permanent incisors as well. Symptoms and signs include demarcated opacities of various colors, post-eruptive enamel deterioration, atypical caries and restorations, hypersensitivity, tooth loss due to MIH, and difficulty in achieving anesthesia. A detailed review of the scientific literature shows that there are many studies evaluating different treatment approaches for permanent first molars affected by MIH. On the other hand, there are very few scientific studies evaluating treatment approaches for affected incisors in patients with MIH. Most of these studies consist of case reports or series. White/creamy and/or yellow/brown demarcated opacities are commonly observed in affected incisors in patients with MIH. While these opacities increase the susceptibility of enamel to deterioration and dental caries, they also cause aesthetic problems and related psychosocial consequences. Treatment methods, such as resin infiltration, microabrasion, and/or dental bleaching, have been proposed for aesthetic and restorative purposes in affected incisors in patients with MIH. Additionally, various approaches to increase mineral content and relieve hypersensitivity have been recommended. The number of randomized controlled and prospective studies is quite low, but many case reports and case series have been encountered. The purpose of this review was to provide a comprehensive overview of the different treatment management modalities for permanent incisors affected by MIH. As a result, while resin infiltration, dental bleaching, microabrasion, and/or etch–bleach–seal techniques are preferred for aesthetic and restorative purposes in these teeth, it has been observed that agents containing casein phosphopeptide amorphous calcium phosphate, casein phosphopeptide amorphous calcium fluoride phosphate, fluoride, and calcium glycerophosphate increase the mineral content. Additionally, studies have reported that ozone and low-level laser therapy, in addition to these remineralizing agents, reduce hypersensitivity in these teeth. Although the findings of this review indicate that the level of evidence for current approaches is not high, clinicians may prefer one or more of the treatment approaches mentioned in this article based on experience and patient expectations.

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Section: Approaches To Relieving Hypersensitivitymentioning

confidence: 99%

Treatment Strategies for Incisors of Children Affected by Molar Incisor Hypomineralization: A Narrative Review

Sezer,

Çarıkçıoğlu

2024

Oral

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“…Both studies propose treatment protocols and clinical evaluations to determine the efficacy of these therapies, recognizing the importance of hypersensitivity management for the overall success of MIH treatment [79,88].…”

Section: Therapy For Dental Hypersensitivity and Pulpotomymentioning

confidence: 99%

Treatment Approaches to Molar Incisor Hypomineralization: A Systematic Review

Inchingolo,

Viapiano

et al. 2023

JCM

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Aim: This systematic review aimed to comprehensively evaluate the available literature on treating molar incisor hypomineralization (MIH) or enamel hypomineralization published between 2013 and 2023, focusing on identifying relevant studies and their characteristics. Materials and Methods: The search process encompassed reputable academic databases, including PubMed, Scopus, Cochrane Library, and Web of Science, using a precise keyword strategy (“((molar incisor hypomineralization) OR (enamel hypomineralization)) AND (treatment)”). A total of 637 articles were initially retrieved, followed by a strict selection process adhering to PRISMA guidelines. The inclusion criteria encompassed Randomized Control Trials (RCTs), case series with more than five clinical cases (CSs), studies involving human participants, availability as free full-text or accessible with university credentials, and English-language publications. Exclusion criteria included systematic or literature reviews, editorials, single-case reports, studies conducted in vitro, those involving animals, paid articles, and non-English-language publications. Results: The search yielded 864 articles, of which 23 met the stringent inclusion criteria after a meticulous selection process. These studies will serve as the basis for a comprehensive analysis of MIH treatment approaches. The systematic review ensures the quality and relevance of the chosen studies for a detailed assessment of MIH treatment strategies. Conclusions: This systematic review will provide valuable insights into the characteristics of selected studies, patient profiles, and available treatment options for molar incisor hypomineralization, contributing to a better understanding of this dental condition’s management.

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