The contributions of dietary protein and mineral to the healing of experimental fractures. A biomechanical study.

Factores de riesgo que afectan la fusión en el tratamiento de la inestabilidad en la columna lumbar

“…Lo más importante es que pueden ser detectados desde la consulta externa, lo que en algunos casos la probabilidad de una pseudoartrosis ser prevenible, tal es el caso de la propia obesidad, acompañada de una valoración especifica del IMC, la hipoalbuminemia y la linfopenia [6][7][8][9] . La obesidad como factor único puede incrementar un 5% la probabilidad de una pseudoartrosis, que si le agregamos factores como la hipoalbuminemia, este se puede incrementar hasta un 42% la probabilidad de un resultado no deseado 8,10,11 . La densidad ósea también nos marca una probabilidad del 33% y la edad mayor de 60 años puede llegar a ser siete veces mayor la probabilidad de que no exista una fusión en la zona de la cirugía 7,12,13 .…”

Does The Nutritional Status Changes The Healing Outcome Of Simple Diaphysel Tibial Fractures In Adults: A Prospective Cohort Study

“…Similar to our result, they also found statistically insignificant association of fracture healing outcomes with nutritional status of the patients. But on other hand, Day et al 13 , Einhorn et al 14 & Guarniero et al 30 found the significant association of nutritional status with tibial fracture healing in rats and concluded that nutrition significantly directs the fracture healing in tibia.…”

“…[8][9] Many of the factors are responsible for fracture impairment, [10][11] including nutritional status of the patient. [12][13][14][15] Based on above findings, we planned the study to correlate the tibial fracture healing outcomes with nutritional status by taking serum albumin and serum ferritin as a nutritional status indicator of the patients and hypothesised that the fracture healing outcomes of tibial fractures was significantly associated with these nutritional status parameters of the treating patients.…”

“…Fractures impairment may be caused by several factors such as extensive soft tissue damage, the presence of a gap at the fracture site, poor mechanical stability, open fractures, administration of pharmacological agents, such as NSAIDs and smoking, etc [10][11] . The potential role of nutritional health in the fracture healing outcomes among individuals also known [12][13][14][15] . But till now, they are not in use as a prognostic marker, in parallel to clinic-radiological diagnosis.…”

“…Some authors have used albumin levels alone as a laboratory indicator for malnutrition in orthopaedic patients [16][17][18] . Many studies had been correlated protein depletion with increased mortality and morbidity, wound infection, surgical failure, sepsis as well as impaired fracture union and wound healing 19,[12][13][14][15] . Koval et al in a study also demonstrated that albumin level of < 3.5 g/dl was predictive of delay of fracture to heal, increased length of hospital stay as well as their mortality rate 20 .…”