The contribution of 18F-FDG PET/CT in a patient with cutaneous metastases of squamous cell carcinoma of the penis

Banzo, J.; Ubieto, M.A.; Andrés, A.; Tardín, L.; Rambalde, E.F.; Cáncer, L.; Razola, P.; Prats, E.

doi:10.1016/j.remnie.2014.06.017

Cited by 1 publication

(2 citation statements)

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“…[7] SCC is the most common malignant histology affecting 50-70 years old men, apart from sarcoma, basal cell carcinoma, and malignant melanomas. [1] SCC penis generally metastasizes distantly to the lung, liver, brain, bones, heart, adrenals, eye, [1] and skin, [2] and locoregionally to inguinal and pelvic LNs. However, bibliographical search in online database sites such as PubMed, PubMed-Central, Medline, and Google Scholar did not show any report on exclusive upfront SCLN metastasis from PC.…”

Section: Discussionmentioning

confidence: 99%

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Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by 18F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case

et al. 2021

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Carcinoma penis is a rare malignancy accounting 0.5%–1% of cases in the developed countries with a slightly higher incidence in the developing nations. Slow locoregional progression is characteristic of penile carcinoma (PC) and distant metastases are very uncommon. We hereby report a case of highly aggressive squamous cell PC in a 46-year-old male with fulminant upfront distant dissemination to left supraclavicular lymph nodes (LNs) without involving the inguinal and pelvic nodes detected by whole-body 18 F-fluorodeoxyglucose positron-emission tomography scan. The scan also detected lytic destructive lesion involving the pelvic and adjacent bones with infiltration of skeletal muscles. He was treated with palliative radiotherapy to the wight-bearing sites followed by systemic chemotherapy. A thorough review of literature reveals that our case may be one of the rarest cases ever reported in world literature where an asymptomatic PC presents with upfront supraclavicular LN metastasis bypassing the inguinal, pelvic, and retroperitoneal LN chains.

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Section: Discussionmentioning

confidence: 99%

“…[1] PC metastasizes most commonly to superficial and deep inguinal, external and internal iliac, and para-aortic lymph-nodes (LN). Lung, liver, brain, bones, [1] and skin [2] are the distant organs affected. However, direct supraclavicular LN (SCLN) involvement from PC without affecting the regional lymphatics is rarely heard of.…”

Section: Introductionmentioning

confidence: 99%