The continuous performance test revisited with neuroelectric mapping: impaired orienting in children with attention deficits

Leeuwen, Theo H. van; Steinhausen, H.‐C.; Overtoom, C.C.E.; Pascual-Marqui, Roberto D.; Klooster, B. Van't; Rothenberger, Aribert; Sergeant, Joseph A.; Brandeis, Daniel

doi:10.1016/s0166-4328(97)00173-3

Cited by 182 publications

(190 citation statements)

References 40 publications

Supporting

Mentioning

159

Contrasting

Unclassified

Order By: Relevance

“…This is also consistent with studies of event-related potentials (ERPs) which have shown reduced amplitudes to attentional orienting cues over posterior brain regions, consistent with dysfunction of the posterior parietal attentional system. [21][22][23] We therefore suggest that right parietal dysfunction in ADHD-CT is development-stage independent, observed both in adolescents 3 and children, and contributes to known clinical and behavioural deficits such as impairments in the control of attention 39 and spatial working memory. 12 The frontal areas of activation in both ADHD-CT and healthy children were considerably less than those in both ADHD-CT and healthy adolescents, Listed are peak voxels (P uncorrected < 0.005) that are located within significant activation clusters (P corrected < 0.05).…”

Section: Discussionmentioning

confidence: 82%

“…Earlier studies of EEG event-related potentials also provide considerable evidence for dysfunction within a posterior attentional system, consistent with deficits in parietal cortex mechanisms for attentional orienting. [21][22][23] Taken together, these findings currently suggest widespread dysfunction of frontal, striatal and parietal neural circuits in adolescents with ADHD compared to controls that can be inferred by either under-or overactivation depending on the cognitive processes involved in the experimental task. At present, it remains unclear whether the decreased right fronto-striatal-parietal activation observed during mental rotation in our study of adolescents with ADHD-CT is developmental stage specific or independent.…”

Section: Introductionmentioning

confidence: 84%

See 1 more Smart Citation

Right parietal dysfunction in children with attention deficit hyperactivity disorder, combined type: a functional MRI study

et al. 2007

View full text Add to dashboard Cite

Attention deficit hyperactivity disorder, combined type (ADHD-CT) is associated with spatial working memory deficits. These deficits are known to be subserved by dysfunction of neural circuits involving right prefrontal, striatal and parietal brain regions. This study determines whether decreased right prefrontal, striatal and parietal activation with a mental rotation task shown in adolescents with ADHD-CT is also evident in children with ADHD-CT. A crosssectional study of 12 pre-pubertal, right-handed, 8-12-year-old boys with ADHD-CT and 12 prepubertal, right-handed, performance IQ-matched, 8-12-year-old healthy boys, recruited from local primary schools, was completed. Participants underwent functional magnetic resonance imaging while performing a mental rotation task that requires spatial working memory. The two groups did not differ in their accuracy or response times for the mental rotation task. The ADHD-CT group showed significantly less activation in right parieto-occipital areas (cuneus and precuneus, BA 19), the right inferior parietal lobe (BA 40) and the right caudate nucleus. Our findings with a child cohort confirm previous reports of right striatal-parietal dysfunction in adolescents with ADHD-CT. This dysfunction suggests a widespread maturational deficit that may be developmental stage independent.

show abstract

Section: Discussionmentioning

confidence: 82%

Section: Introductionmentioning

confidence: 84%

Right parietal dysfunction in children with attention deficit hyperactivity disorder, combined type: a functional MRI study

et al. 2007

View full text Add to dashboard Cite

show abstract

“…The primary aim of the pilot study is to establish whether it is feasible for endusers to conduct a continuous performance test (CPT) [14] whilst their physical activity is measured using the in-built motion sensors (accelerometer, gyroscope) [15]. This type of psychometric test involves presenting a sequence of letters (or alternatively a series of images or audio cues) and asking the user to respond when a specified target occurs e.g.…”

Section: Snappy App: Attention Deficit Hyperactivity Disorder Assessmmentioning

confidence: 99%

Developing mHealth Apps with Researchers: Multi-Stakeholder Design Considerations

Craven

Lang

Martin

2014

Design, User Experience, and Usability. User Experience Design for Everyday Life Applications and Services

View full text Add to dashboard Cite

Abstract. The authors have been involved with developing a number of mHealth smartphone Apps for use in health or wellness research in collaboration with researchers, clinicians and patient groups for clinical areas including Sickle Cell Disease, Attention Deficit Hyperactivity Disorder, asthma and infertility treatment. In these types of applications, end-users self-report their symptoms and quality of life or conduct psychometric tests. Physiological data may also be captured using sensors that are internal or external to the device.Following a discussion of the multiple stakeholders that are typically involved in small scale research projects involving end-user data collection, four Apps are used as case studies to explore the issue of non-functional requirements.Keywords: m-Health, Requirements Engineering, Software Engineering, User experience, Ethical issues in DUXU, Healthcare/Medical systems and DUXU, Management of DUXU processes, Medical/healthcare and DUXU, Mobile products and services BackgroundMobile health (mHealth) applications (Apps) based on cellular phones, Smartphones and tablet computers are a rapidly growing trend in healthcare [1][2][3]. Healthcare researchers are increasingly turning to mobile apps for data collection as it is seen as a quick, easy way to obtain data from end-users (patients, carers or members of the public) in their everyday environment, using devices that users either own themselves or are becoming increasingly familiar with.

show abstract

“…Studies using structural and functional brain imaging, electrophysiology and transcranial magnetic stimulation have shown various abnormalities in frontal, temporal, and parietal cortical regions, basal ganglia (striatum), callosal areas, and cerebellum [13,14,23,28,29,47,102,111,126,157,163,176,190]. The morphological abnormalities seem to be evident early, non-progressive, and not a result of stimulant treatment [29].…”

Section: Influences On Pathogenesismentioning

confidence: 99%

European clinical guidelines for hyperkinetic disorder ? first upgrade

Taylor

Döpfner

Sergeant

et al. 2004

European Child & Adolescent Psychiatry

Self Cite

492

452

View full text Add to dashboard Cite

■ Abstract Background The validity of clinical guidelines changes over time, because new evidencebased knowledge and experience develop. Objective Hence, the European clinical guidelines on hyperkinetic disorder from 1998 had to be evaluated and modified. Method Discussions at the European Network for Hyperkinetic Disorders (EUNETHYDIS) and iterative critique of each clinical analysis. Guided by evidence-based information and based on evaluation (rather than metaanalysis) of the scientific evidence a group of child psychiatrists and psychologists from several European countries updated the guidelines of 1998. When reliable information is lacking the group gives a clinical consensus when it could be found among themselves. Results The group presents here a set of recommendations for the conceptualisation and management of hyperkinetic disorder and attention deficit/hyperactivity disorder (ADHD). Conclusion A general scheme for practice in Europe could be provided, on behalf of the European Society for Child and Adolescent Psychiatry (ESCAP).

show abstract

The continuous performance test revisited with neuroelectric mapping: impaired orienting in children with attention deficits

Cited by 182 publications

References 40 publications

Right parietal dysfunction in children with attention deficit hyperactivity disorder, combined type: a functional MRI study

Right parietal dysfunction in children with attention deficit hyperactivity disorder, combined type: a functional MRI study

Developing mHealth Apps with Researchers: Multi-Stakeholder Design Considerations

European clinical guidelines for hyperkinetic disorder ? first upgrade

Contact Info

Product

Resources

About