The continuing scourge of congenital syphilis in 21st century: A case report

Managing congenital syphilis again? The more things change …

“…Most affected infants are asymptomatic at birth, with two-thirds developing symptoms by 3-8 weeks. Almost all exhibit symptoms by 3 months of age [18].…”

Early congenital syphilis presented with exclusive bending pain of extremity: Case report

“…The clinical manifestations of congenital syphilis occur in an early and a late form 5 . Early congenital syphilis occurs before the age of 2 years and can often be viewed as an exaggeration of acquired secondary syphilis 6,7 . Diagnosis of early congenital syphilis is problematic because more than half of all infants are asymptomatic, and signs in symptomatic infants may be subtle and nonspecific.…”

Neonatal Cholestasis

“…Perinatal infection is less frequent but may occur during delivery in the presence of maternal genital lesions. 78 The liver histologic findings are usually a characteristic centrilobular fibrosis with mononuclear infiltration or a more typical histology of neonatal cholestasis. As a general rule the longer the interval between T. pallidum infec tion and pregnancy, the more benign is the neonate' s outcome.…”