The Content of Structural and Trace Elements in the Knee Joint Tissues

Roczniak, Wojciech; Brodziak-Dopierała, Barbara; Cipora, Elżbieta; Mitko, Krzysztof; Jakóbik‐Kolon, Agata; Konieczny, Magdalena; Babuśka–Roczniak, Magdalena

doi:10.3390/ijerph14121441

Cited by 10 publications

(8 citation statements)

References 56 publications

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“…Mean concentration of Pb in the knee joint elements vary between 0.20–4 mg∙kg −1 dm [16,17]. Our study has shown that the mean concentration of this element in the infrapatellar fat pad is lower than in the bone tissue, and amounts to 0.51 mg∙kg −1 dm.…”

Section: Discussionmentioning

confidence: 76%

“…Mean level of Mg in the knee joint varies from 78 to 1600 mg∙kg −1 dm [15,16]. Our study reports the infrapatellar fat pad concentration of the element at the level of 46.57 mg∙kg −1 dm, much lower than its concentration in the bone tissue, which, because of the longer time it needs to form, may reflect chronic exposure and provide a basis for indirect assessment of the extent of environmental exposure.…”

Section: Discussionmentioning

confidence: 80%

“…Based on the results of other studies, the mean concentration of Ca in the knee joint components usually varies between 3000 and 5050 mg∙kg −1 dm [15,16], whereas its concentration in the infrapatellar fat pad was lower than the relevant Ca levels in the anterior cruciate ligament and the meniscus, where it amounts to 1290.38 mg∙kg −1 dm. The discrepancy between the figures may be due to structural inhomogeneity of these components.…”

Section: Discussionmentioning

confidence: 99%

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Concentration of Selected Elements in the Infrapatellar Fat Pad of Patients with a History of Total Knee Arthroplasty

Ciosek

Danuta

Natalia

et al. 2019

IJERPH

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In the period of long development, the human body adapted to specific concentrations of trace elements. Any changes in the trace element content manifesting in a deficiency or excess of metals in the human body may impair the functioning of the skeletal and articular system and of the organs, and may also predispose the body to the development of diseases, i.e., osteoporosis. Our study aimed to analyze the concentrations of calcium (Ca), magnesium (Mg), fluorides (F-), and lead (Pb) in the infrapatellar fat pad (Hoffa’s fat pad) of subjects who had undergone a total knee replacement (TKR) surgery. We also endeavored to establish how concentration levels of those elements are affected by selected biological and environmental factors. The studied group comprised 48 residents of Western Pomerania Province: 34 women (n = 34) aged 56–87 and 12 men (n = 12) aged 59–85. Concentration levels of Ca, Mg, and Pb were established using inductively coupled plasma-atomic emission spectrometry (ICP-AES). A Thermo Orion ion-selective electrode was applied for measuring F- concentration. Subjects aged 75–87 showed higher Mg concentration values than those aged 56–74. Big city residents and smokers were found to have higher infrapatellar fat pad Mg concentration than their non-smoking counterparts and small town dwellers. Of all the elements whose concentrations we analyzed in our studies, only magnesium was found to correlate with smoking, place of residence, and age. Our findings regarding the quantities of selected elements in the infrapatellar fat pad may be used for the interpretation and analysis of biological, morphological, and mechanical changes in the human body.

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Section: Discussionmentioning

confidence: 76%

Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Concentration of Selected Elements in the Infrapatellar Fat Pad of Patients with a History of Total Knee Arthroplasty

Ciosek

Danuta

Natalia

et al. 2019

IJERPH

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“…Kosik-Bogacka et al ( 33 ) noticed that Pb concentrations in the anterior cruciate ligament, meniscus and cartilage were higher in men than in women, while significant difference of Pb concentration between men and women only existed in meniscus. Roczniak et al ( 40 ) noted significantly higher Pb concentrations in the femur, tibia and meniscus of men (3.22, 3.99, and 0.53 mg/kg dw, respectively) compared to women (2.41, 2.16, and 0.24 mg/kg dw, respectively). However, this study found higher Pb concentrations in the knee joint structures of women as compared to men.…”

Section: Discussionmentioning

confidence: 98%

Factors Affecting the Aluminum, Arsenic, Cadmium and Lead Concentrations in the Knee Joint Structures

Xiong

et al. 2021

Front. Public Health

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Background: Toxic elements, such as aluminum (Al), arsenic (As), cadmium (Cd), and lead (Pb), are persistent environmental pollutants that can cause adverse effects on the health of exposed individuals. Bone is one of the primary target organs of accumulation and potential damage from toxic elements.Objectives: This study was performed to determine the Al, As, Cd, and Pb concentrations in the femoral cancellous bone, femoral cartilage, anterior cruciate ligament, meniscus, tibial cartilage, tibial cancellous bone and infrapatellar fat pad. Furthermore, the aim of this study was to explore the relationships between toxic element concentrations and related factors such as gender, age, place of residence, hypertension and diabetes, and to determine the correlations among these toxic elements in knee joint structures.Methods: The samples used this study were collected from 51 patients following total knee arthroplasty. The Al, As, Cd, and Pb concentrations were determined using inductively coupled plasma optic emission spectrometry.Results: Significant differences were found in the Al, As, Cd, and Pb concentrations among the knee joint structures. Cd concentration in the tibial cancellous bone in women was significantly higher than in men. Pb concentration in the infrapatellar fat pad of urban patients was significantly higher as compared to rural patients. Al concentrations in the femoral cancellous bone, femoral cartilage, anterior cruciate ligament, meniscus and tibial cartilage were significantly higher in patients living in urban areas than in rural areas. As concentration in the tibial cancellous bone of diabetic patients was significantly higher compared to non-diabetic patients. In addition, significant Spearman's positive correlations were found between Al and Pb in the knee joint structures.Conclusion: The obtained results of the investigated toxic elements may serve as a basis for establishing the reference values of Al, As, Cd, and Pb in the knee joint structures. The results reported in the study provides novel data regarding the relationships between the toxic element concentrations and gender, age, place of residence, hypertension and diabetes in the studied structures of knee joint. Furthermore, new interactions among these toxic elements were noted.

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“…The current study revealed that the level of chromium accumulated in the bone tissue was similar to its content in the connective tissue. Thus, chromium accumulation is opposite to that of cadmium [ 23 , 24 ]. In the study concerning the content of chromium in the hip joint, its level in the spongy bone was approximately 3 times higher compared to other parts of this joint.…”

Section: Discussionmentioning

confidence: 99%

Analysis of the Content of Chromium in Certain Parts of the Human Knee Joint

Roczniak

Brodziak-Dopierała

Cipora

et al. 2018

IJERPH

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Chromium is an essential microelement in the human body. It exerts an effect on bones by modulating their biochemical parameters: alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP). With considerable accumulation of chromium in the skeleton, the activity of alkaline phosphatase was found to decrease, which affected bone formation rate. The study objective was to analyze chromium content in the knee tissues. Tissues for analysis were obtained during endoprosthesoplasty of the knee joint and included tibia, femur, and meniscus tissues. Samples were collected from 50 patients, including 36 women and 14 men. The analysis was performed using the inductively coupled plasma atomic emission spectroscopy (ICP-AES) method, by means of a Varian 710-ES apparatus. The results revealed no significant differences in the content of chromium in the knee joint tissues between women and men. The highest level of chromium was found in the femoral bone of the knee joint, then in the meniscus, and was lowest in the tibia, although the differences were statistically insignificant. Chromium content increased with age.

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The Content of Structural and Trace Elements in the Knee Joint Tissues

Cited by 10 publications

References 56 publications

Concentration of Selected Elements in the Infrapatellar Fat Pad of Patients with a History of Total Knee Arthroplasty

Concentration of Selected Elements in the Infrapatellar Fat Pad of Patients with a History of Total Knee Arthroplasty

Factors Affecting the Aluminum, Arsenic, Cadmium and Lead Concentrations in the Knee Joint Structures

Analysis of the Content of Chromium in Certain Parts of the Human Knee Joint

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