The Content of Sh-Groups in Plasma of Peripheral Blood of Sheep Exposed to Chronic Intake of Lead From Diet

Abstract

We studied the content of the SH-groups in plasma of peripheral blood of sheep, which during 90 days received the nitrate of lead in the diet at concentrations of 5 (1 MRL), 25 (5 MRL) and 150 mg/kg of feed (30 MRL). It is shown that chronic intake of lead in the organism of the sheep leads to a decrease in content of SH-groups in peripheral blood plasma. The most pronounced changes were noted when the concentration of lead in the diet was 25 mg/kg (5 MRL) and 150 mg/kg feed (30 MRL). It is supposed that with increasing of concentration of lead in the organs and tissues of mammals are initiated the processes of formation of reactive oxygen species that lead to oxidative modification of proteins and lipids.