The Construction of the Self-Induced Sal System and Its Application in Salicylic Acid Production
Xin Jin,
Yaping Gao,
Xuanmu Chen
et al.
Abstract:The design and construction of more complex and delicate genetic control circuits suffer from poor orthogonality in quorum sensing (QS) systems. The Sal system, which relies on salicylic acid as a signaling molecule, is an artificially engineered regulatory system with a structure that differs significantly from that of natural QS signaling molecules. Salicylic acid is an important drug precursor, mainly used in the production of drugs such as aspirin and anti-HIV drugs. However, there have been no reports on … Show more
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