Abstract:Postpartum depression (PPD) is a major health problem, and in recent years its prevalence has been increasing. The physiological changes and mood disorders associated with pregnancy and the postnatal period are mainly due to a hormonal imbalance. Destabilizing the mother's hypothalamic pituitary adrenal (HPA) axis increases the susceptibility to depression, probably by significantly increasing plasma cortisol. Stress and inflammation play a key role in postpartum. Also, lactogenic hormones have antidepressant … Show more
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