Abstract:Objective:Metabolic syndrome (MetS) is the principal pathological consequence of obesity. Metabolome dysfunctions lead to multi-organ failure and cardiovascular complications, especially in the elderly. The metabolome is the output of genes-environment interaction and the epigenetic modifications act as their linker. So, it is reasonable a possible interplay between metabolomics and epigenetics. MetS prevalence increases sharply with age, especially in women, reaching in postmenopause a comparable prevalence t… Show more
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