Let (M m , g) be a closed Riemannian manifold (m ≥ 2) of positive scalar curvature and (N n , h) any closed manifold. We study the asymptotic behaviour of the second Yamabe constant and the second N −Yamabe constant of (M × N, g + th) as t goes to +∞. We obtain). If n ≥ 2, we show the existence of nodal solutions of the Yamabe equation on (M × N, g + th) (provided t large enough). When sg is constant, we prove that limt→+∞ Y 2. Also we study the second Yamabe invariant and the second N −Yamabe invariant.