The concept of chronotypes and its clinical importance for depressive disorders

Müller, Matthias J.; Haag, Anja

doi:10.1177/0091217417749787

Cited by 18 publications

(10 citation statements)

References 78 publications

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“…Early chronotype (morning type, advanced sleep phase) and late chronotype (evening type, delayed sleep phase) are two extreme types of chronotypes 4 . Previous studies have reported that individuals with late chronotype are more likely to have depression or depressive symptoms 5 , 6 .…”

Section: Introductionmentioning

confidence: 95%

Sex differences in the association between chronotype and risk of depression

Kim

Han

Heo

et al. 2020

Sci Rep

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Information on sex differences in the association between chronotype and depression is scarce. We aimed to investigate these differences using data from the Korea National Health and Nutrition Examination Survey in 2016. Chronotypes were categorised based on mid-sleep time on free days corrected by sleep debt accumulated on workdays (MSFsc): early type, < mean MSFsc − 1 standard deviation (SD); intermediate type, between mean MSFsc − 1 SD and MSFsc + 1 SD; and late type, > mean MSFsc + 1 SD. A Patient Health Questionnaire-9 score of ≥ 10 indicated depression. Among 5550 non-shift working adults aged 19–80 years, the prevalence rates of depression in the early, intermediate, and late chronotype groups were 7.4%, 4.5%, and 9.3%, respectively. Women with late chronotype (odds ratio [OR] = 2.9, 95% confidence interval [CI] = 1.8–4.7) showed a higher risk of depression than women with intermediate chronotype after adjusting for covariates. Women with early chronotype did not show a significant difference in depression risk (OR = 1.3, 95% CI = 0.9–2.0). In conclusion, late chronotype is associated with an increased risk of depression in women but not in men. Early chronotype is not associated with depression in women or men.

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Section: Introductionmentioning

confidence: 95%

Sex differences in the association between chronotype and risk of depression

Kim

Han

Heo

et al. 2020

Sci Rep

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“…The chronotype of an individual is strongly influenced by genes from birth (Barclay, Eley, Buysse, Archer, & Gregory, 2010; Koskenvuo, Hublin, Partinen, Heikkila, & Kaprio, 2007). In addition, light influences circadian rhythms at all ages (Müller & Haag, 2017), and social life/personal habits emerge as important predictors of sleep schedules in adolescence (Adan et al, 2012). Generally, chronotype changes systematically with age and reaches the maximum of eveningness propensity at around the age of 20 years (Roenneberg et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Chronotype and depressive symptoms: A moderated mediation model of sleep quality and resilience in the 1st‐year college students

et al. 2020

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Objective: Depression is highly prevalent among 1st-year college students, and evening chronotype is an important risk factor associated with depression. This study investigates the mediating role of sleep quality and the moderating role of resilience between chronotype and depressive symptoms. Methods: A total of 4531 students were included in this cross-sectional study. Mediation and moderated mediation models were applied. Results: The association between chronotype and depressive symptoms was partially mediated by sleep quality, and the direct and indirect effects were moderated by resilience. The negative correlation between chronotype and depressive symptoms was significant in students with low levels of resilience compared with moderate/high levels. The positive correlation between sleep quality and depressive symptoms was strongest in low-level resilience students. Conclusion: This study reveals that greater eveningness is associated with poorer sleep quality among 1st-year college students, which may lead to severer depression, and highlights the importance of resilience training in reducing depressive symptoms.

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“…The cyclic factor that determines this preference was called a circadian preference, which largely depends on an individual's endogenous component (1). Circadian preference was a continuum but was usually divided into three chronotypes: morning types (M-types), neutral types (N-types), and evening types (E-types) (2). At the onset of adolescence, a sharp shift toward E-types starts, reaching its peak at the end of youth, followed by a steady shift toward M-types as the aging process occurs (3,4).…”

Section: Introductionmentioning

confidence: 99%

Chronotype, Sleep, and Depressive Symptoms Among Chinese College Students: A Cross-Sectional Study

Xie

Tao

et al. 2020

Front. Neurol.

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Objective: To describe the prevalence of chronotype and depressive symptoms among Chinese college students and to examine the association between chronotype and depressive symptoms.Methods: From April to May 2019, a cross-sectional survey was conducted among 1,179 Chinese college students from 2 universities in Anhui and Jiangxi provinces. A total of 1,135 valid questionnaires were collected, the valid response rate was 98.6%. The questionnaire investigated age, gender, major, height, weight, only child status, living place, self-reported family economy, and self-reported study burden. The chronotype was assessed by the Morning and Evening Questionnaire (MEQ). Depressive symptoms and sleep quality were evaluated by the Patient Health Questionnaire 9 (PHQ-9) and the Pittsburgh Sleep Quality Index (PSQI), respectively. A Chi-square test was used to examine the proportion of depressive symptoms among Chinese college students with different demographic characteristics. The generalized linear model was used to analyze the relationships between chronotype and depressive symptoms.Results: The proportion of morning types (M-types), neutral types (N-types), and evening types (E-types) of college students were 18.4, 71.1, and 10.5%, respectively. The proportion of mild depression, moderate depression, and moderate to severe depression of participants were 32.4, 6.0, and 4.2%, respectively. Compared to the M-types, after controlled for age, gender, major, sleep quality, self-reported study burden, father's education level, and self-reported family economy, depressive symptoms were positively correlated with E-types (OR = 2.36, 95% CI: 1.49–3.73).Conclusions: There was a significant association between chronotype and depressive symptoms among Chinese college students. Further longitudinal studies were needed to clarify the causal relationship between chronotype and depressive symptoms.

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The concept of chronotypes and its clinical importance for depressive disorders

Cited by 18 publications

References 78 publications

Sex differences in the association between chronotype and risk of depression

Sex differences in the association between chronotype and risk of depression

Chronotype and depressive symptoms: A moderated mediation model of sleep quality and resilience in the 1st‐year college students

Chronotype, Sleep, and Depressive Symptoms Among Chinese College Students: A Cross-Sectional Study

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