The concentration of manganese, iron, and strontium in hip joint bone obtained from patients undergoing hip replacement surgery

Budis, Halina; Kalisińska, Elżbieta; Lanocha, Natalia; Kosik-Bogacka, Danuta; Sokolowski, Sebastian; Dobiecki, Konrad; Kołodziej, Łukasz; Bohatyrewicz, Andrzej

doi:10.1016/j.jtemb.2013.07.004

Cited by 22 publications

(28 citation statements)

References 32 publications

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“…Zn levels were significantly lower in females than males, while Mn levels were significantly higher. Contrary to previous reports, we detected no other correlation or Ca:Mg-ratio variation according to levels of other trace elements 40–42…”

Section: Discussioncontrasting

confidence: 99%

Comparison of bone tissue trace-element concentrations and mineral density in osteoporotic femoral neck fractures and osteoarthritis

Karaaslan

Mutlu

Mermerkaya

et al. 2014

CIA

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PurposeThis study examined the role of trace elements in osteoporosis by comparing the trace-element concentrations in bone and the radiographic bone density and bone mineral density (BMD) of patients with osteoporotic femur fractures and osteoarthritis.Patients and methodsThe study enrolled 30 patients operated on for proximal femoral fractures after falls, and another 30 patients undergoing hip arthroplasty at the same center for hip osteoarthritis. Bone samples were obtained during the surgical procedures. The density of the bone samples was assessed using computed tomography and the Hounsfield scale. The levels of Ca(II), Mg(II), and other trace elements in the bone samples were determined using flame atomic absorption spectrometry and inductively coupled plasma mass spectrometry. In addition, BMD, Z-scores, and T-scores were measured in the unaffected hips of all patients using dual-energy X-ray absorptiometry.ResultsMagnesium (1,908±507 versus 2,540±435, P<0.05), calcium (10.4±3.5 versus 13.9±3.7, P<0.05), and zinc (2,342±1,252 versus 3,145±1,604, P<0.05) μg g−1, levels were significantly lower in the bone samples in the fracture group. The groups did not differ in the other biochemical parameters. All dual-energy X-ray absorptiometry findings were significantly worse in the fracture group than in the osteoarthritis group. However, the groups did not differ in femoral neck density assessed radiologically using the Hounsfield scale. The following parameters were negatively correlated with age: magnesium, r=−0.436, P<0.001; calcium, r=−0.331, P=0.01; T-score, r=−0.381, P=0.003; Z-score, r=−0.267, P=0.043; and BMD, r=−0.365, P=0.004.ConclusionCa(II), Mg(II), and Zn(II) appear to play important roles in bone breakdown/synthesis. Further studies of the roles of trace elements in the etiology and treatment of osteoporosis are warranted. We found decreased bone levels of Ca, Mg, and Zn in patients with osteoporotic fractures compared to subjects with osteoarthritis.

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Section: Discussioncontrasting

confidence: 99%

Comparison of bone tissue trace-element concentrations and mineral density in osteoporotic femoral neck fractures and osteoarthritis

Karaaslan

Mutlu

Mermerkaya

et al. 2014

CIA

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“…In respect to the gender of the participants, we did not observe statistically significant differences in Fe concentration in studies of the knee joint. Budis et al [48] found similar Fe concentrations in the cartilage and spongy bone in men and women. Brodziak-Dopierała et al [49] also noted no statistically significant differences in Fe concentration in the meniscus between men and women.…”

Section: Discussionmentioning

confidence: 86%

“…In the spongy bone of the patients from northwestern Poland, the Fe concentration was 56.032 mg/kg dw. Łanocha et al [47] and Budis et al [48] found lower Fe level in patients from the same area (43.9 and 43 mg/kg dw, respectively). The difference may result from the different study materials.…”

Section: Discussionmentioning

confidence: 88%

“…The difference may result from the different study materials. The spongy bone in our study were obtained from the knee joint, and in the studies by Łanocha et al [47] and Budis et al [48] they were taken from the hip joint. In respect to the gender of the participants, we did not observe statistically significant differences in Fe concentration in studies of the knee joint.…”

Section: Discussionmentioning

confidence: 97%

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Impact of Varied Factors on Iron, Nickel, Molybdenum and Vanadium Concentrations in the Knee Joint

Kot

Kosik-Bogacka

Ziętek

et al. 2020

IJERPH

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The aim of this study was to determine the concentrations of iron, nickel, molybdenum, and vanadium in the knee joint. We also examined the relationships between the concentrations of these metals in the knee joint and the influence of varied factors on the concentration of Fe, Ni, Mo, and V. The study of these trace elements is important, because these elements are used alone and in combination in diet supplements, and they are components of biomaterials implanted in medicine. The study materials, consisting of the spongy bone, cartilage, meniscus, anterior cruciate ligament (ACL), and infrapatellar fat pad, were obtained from 34 women and 12 men from northwestern Poland. The concentrations of Ni, Fe, Mo, and V were determined using spectrophotometric atomic absorption in inductively coupled argon plasma (ICP-AES). We found significantly higher Mo concentrations in the ACL of women than men. There was a significant difference in the Mo concentration in the spongy bone between patients from cities with fewer than 100,000 inhabitants and patients from cities with more than 100,000 residents. Iron concentrations in the spongy bone were higher in non-smoking patients and those who did not consume alcohol. Vanadium concentrations were higher in the infrapatellar fat pads in abstainers. In patients who had not undergone arthroscopy surgery, V concentration was lower in cartilage. The concentrations of V in the cartilage and infrapatellar fat pad were higher in osteoporotic patients than in non-osteoporotic patients. There were significant differences in Fe concentrations in the meniscus, with the lowest in osteoporotic patients. We noted lower Mo concentrations in the spongy bone of patients with rheumatoid arthritis. Furthermore, we noted some new interactions among metals in the studied structures of the knee joint. The results reported in this study show the influence of gender, place of residence, smoking, consumption of alcohol, arthroscopy surgery, osteoporosis, and rheumatoid arthritis on the Fe, Ni, Mo, and V concentrations in the studied structures of the knee joint.

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“…What is more, the content of elements in ribs was also determined by Zaichick et al [28], and the content of copper (1.35 µg/g) was low compared to the results obtained in the present study, and the level of zinc was at a similar level (149 µg/g). Budiš et al [29] determined, among others, the content of manganese in heads of femur in patients living in northern Poland, which was in the range 0.12-0.21 mg/kg. In the present authors' research, the indicated manganese content was higher, averaging 0.87 µg/g.…”

Section: Discussionmentioning

confidence: 99%

Participation of migration paths of selected metals in bone intoxication of Upper Silesia inhabitants

Brodziak-Dopierała

Kwapuliński

Wiechuła

et al. 2017

Ann. Acad. Med. Siles.

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WstępCelem pracy była analiza zawartości kadmu, manganu, chromu, ołowiu, cynku i miedzi w tkance kostnej osób zamieszkujących miasta na terenie Górnego Śląska (Bytom, Katowice, Chorzów, Siemianowice Śląskie, Święto-chłowice). Określono również ponadto zależność między zawartością wybranych metali w środowisku i w tkance kostnej.Materiał i metodyMateriał pobierano w Szpitalu Miejskim w Siemianowicach Śląskich. W grupie badanej poddano analizie 53 głowy kości udowej, w tym 43 od kobiet i 10 od mężczyzn. Próbki tkanki kostnej zostały pobrane w trakcie endoprotezoplastyki stawu biodrowego. Badane tkanki pozyskiwane były śródoperacyjnie w trakcie zabiegów endoprotezoplastyki stawu biodrowego. Zawartość kadmu, manganu, chromu, ołowiu, cynku i miedzi oznaczano za pomocą metody atomowej spektrofotometrii absorpcyjnej za pomocą aparatu Pye Unicam SP-9.WynikiŚrednia zawartość pierwiastków w tkankach głowy kości udowej przedstawiała się następująco: Cd 0,16 < Ni 0,85 < Mn 0,87 < Cu 3,77 < Cr 5,37 < Zn 82,42 (µg/g).WnioskiIntoksykacja kości metalami z pyłu zawieszonego oraz pyłu wyemitowanego z gleby do powietrza dotyczy głównie mieszkańców Katowic. Porównując te informacje z uzyskanymi wynikami potwierdza się największą zawartość takich metali, jak kadm, miedź, chrom, w tkance kostnej mieszkańców tego miasta.

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The concentration of manganese, iron, and strontium in hip joint bone obtained from patients undergoing hip replacement surgery

Cited by 22 publications

References 32 publications

Comparison of bone tissue trace-element concentrations and mineral density in osteoporotic femoral neck fractures and osteoarthritis

Comparison of bone tissue trace-element concentrations and mineral density in osteoporotic femoral neck fractures and osteoarthritis

Impact of Varied Factors on Iron, Nickel, Molybdenum and Vanadium Concentrations in the Knee Joint

Participation of migration paths of selected metals in bone intoxication of Upper Silesia inhabitants

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