In this paper, we prove the concavity of the Renyi entropy power for nonlinear diffusion equation (NLDE) associated with the Laplacian and the Witten Laplacian on compact Riemannian manifolds with non-negative Ricci curvature or CD(0, m)-condition and on compact manifolds equipped with time dependent metrics and potentials. Our results can be regarded as natural extensions of a result due to Savaré and Toscani [39] on the concavity of the Renyi entropy for NLDE on Euclidean spaces. Moreover, we prove that the rigidity models for the Renyi entropy power are the Einstein or quasi-Einstein manifolds and a special (K, m)-Ricci flow with Hessian solitons. Inspired by Lu-Ni-Vazquez-Villani [34], we prove the Aronson-Benilan estimates for NLDE on compact Riemannian manifolds with CD(0, m)-condition. We also prove the NIW formula which indicates an intrinsic relationship between the second order derivative of the Renyi entropy power N p , the p-th Fisher information I p and the time derivative of the W -entropy associated with NLDE. Finally, we prove the entropy isoperimetric inequality for the Renyi entropy power and the Gagliardo-Nirenberg-Sobolev inequality on complete Riemannian manifolds with non-negative Ricci curvature or CD(0, m)-condition and maximal volume growth condition.