The Composition and Behavior of Capsules around Smooth and Textured Breast Implants in Pigs

Minami, Eliza; Koh, Ivan Hong Jun; Ferreira, José Carlos Ronche; Waitzberg, Ângela Flávia Logullo; Chifferi, Valcir; Rosewick, Tomás Fortoul; Pereira, Max Domingues; Saldiva, Paulo Hilário Nascimento; Figueiredo, Luiz Francisco Poli de

doi:10.1097/01.prs.0000240878.24213.b7

Cited by 56 publications

(40 citation statements)

References 43 publications

(44 reference statements)

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“…Regarding the characteristics of the collagen fibers according to Minami et al 20 and Balderrama et al 10 that found a decline in the amount of type III collagen fibers with increased type I collagen fibers with significant differences, the same result was found in this study from 50 days on.…”

Section: Histological Evaluation Of Capsules Formed By Silicon Implansupporting

confidence: 79%

“…Corroborating Minami et al 20 and Vieira 18 that observed variation in the thickness of the capsule due to increase in the noncollagenous layers (intermediate and internal), in this study this increase also occurred in these layers.…”

Section: Evaluation Of the Thickness Of The Capsulesupporting

confidence: 49%

“…Disagreeing with Hwang et al 19 when saying that the preferential localization of myofibroblasts is in the outer layer of the capsule, in this study, like in Minami et al 20 and Prantl et al 6 , it was found in the inner layer.…”

Section: Evaluation Of Myofibroblastsmentioning

confidence: 58%

“…When analyzed the same fraction area, Minami et al 20 found a greater increase of type I collagen fibers in the smooth implants for textured implants with a significant difference. In this study the textured group had a greater increase of type I collagen fibers in relation to the polyurethane group with statistical significance.…”

Section: Histological Evaluation Of Capsules Formed By Silicon Implanmentioning

confidence: 99%

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Histological evaluation of capsules formed by silicon implants coated with polyurethane foam and with a textured surface in rats

Silva¹,

Ribas-Filho²,

Czeczko³

et al. 2016

Acta Cir. Bras.

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PURPOSE:To assess the capsules formed by silicone implants coated with polyurethane foam and with a textured surface. METHODS:Sixty-four Wistar albinus rats were divided into two groups of 32 each using polyurethane foam and textured surface. The capsules around the implants were analyzed for 30, 50, 70 and 90 days. Were analyzed the following parameters: foreign body reaction, granulation tissue, presence of myofibroblasts, neoangiogenesis, presence of synovial metaplasia, capsular thickness, total area and collagen percentage of type I and III, in capsules formed around silicone implants in both groups. RESULTS:The foreign body reaction was only present in the four polyurethane subgroups. The formation of granulation tissue and the presence of myofibroblasts were higher in the four polyurethane subgroups. Regarding to neoangiogenesis and synovial metaplasia, there was no statistical difference between the groups. Polyurethane group presented (all subgroups) a greater capsule thickness, a smaller total area and collagen percentage of type I and a higher percentage area of type III, with statistical difference. CONCLUSION:The use of polyurethane-coated implants should be stimulated by the long-term results in a more stable capsule and a lower incidence of capsular contracture, despite developing a more intense and delayed inflammatory reaction in relation to implants with textured surface.

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Section: Histological Evaluation Of Capsules Formed By Silicon Implansupporting

confidence: 79%

Section: Evaluation Of the Thickness Of The Capsulesupporting

confidence: 49%

Section: Evaluation Of Myofibroblastsmentioning

confidence: 58%

Section: Histological Evaluation Of Capsules Formed By Silicon Implanmentioning

confidence: 99%

See 2 more Smart Citations

Histological evaluation of capsules formed by silicon implants coated with polyurethane foam and with a textured surface in rats

Silva¹,

Ribas-Filho²,

Czeczko³

et al. 2016

Acta Cir. Bras.

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“…The pseudocapsule is supposed to be thicker the stronger the inflammatory tissue reaction against to the implanted substance is. 11 Thickness tends to decrease over time, as observed in the present study, once the process of cell count decline sets in and only fibroblasts and collagen remain in its composition. There is also a contraction related to the action of myofibroblasts.…”

Section: Discussionsupporting

confidence: 51%

Evaluation of low intensity laser's action on silicone mammary implant pseudocapsules in rats

et al. 2009

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Purpose:To evaluate the effect of low intensity laser on the pseudocapsula contraction that occurs around silicone implants. Methods: 60 male rats divided in two experimental groups received a silicone implant in the subcutaneous of the dorsal region. Group I: animals received implants in the subcutaneous dorsal region and did not receive any treatment; Group II: animals received seven irradiation sessions with low intensity laser after they had received subcutaneous implants. Thirty, 60 and 180 days after the surgery, tonometric evaluation of the implants was conducted. After that, the animals were sacrificed, study material was removed and prepared for histological examination. The thickness of the pseudocapsule and the inflammatory reaction were morphometrically quantified. Data obtained were statistically analyzed using the Variance method, and Tukey's Test(P<0.0 5). Results: Group II animals had significant lower pressure. The histological study did not show a significant difference between the groups, but only a higher number of swollen vessels in Group II. The thickness of pseudocapsule around Group II's implants lower than in Group I. Conclusion:The low intensity laser modify tissue's reparation process around the implants suggesting it may be useful to model contractures that are formed around silicone implants. Key words: Breast Implants. Laser Therapy, Low-Level. Silicones. Rats. RESUMO Objetivo:Avaliar o efeito do laser de baixa intensidade sobre a contração da pseudocápsula que ocorre ao redor de implantes de silicone. Métodos: 60 ratos machos divididos em dois grupos receberam implante de silicone. Grupo I: implante no subcutâneo da região dorsal, sem tratamento após a cirurgia; Grupo II: animais receberam sete sessões de irradiação com laser de baixa intensidade após o implante. Trinta, 60 e 180 dias após a cirurgia, foi feita a tonometria dos implantes, Em seguida, os animais foram sacrificados, removendo-se o material de estudo que foi preparado para exame histológico, avaliando-se morfometricamente a espessura da pseudocápsula e a reação inflamatória. A análise estatistica pela técnica da Análise de Variância e Teste de Tukey (P<0.0 5). Resultados: Pressões significativamente menores foram encontradas nos animais do grupo Grupo II. O estudo histológico não mostrou diferença significativa entre os grupos, destacando-se apenas maior quantidade de vasos intumescidos no Grupo II. A espessura da pseudocápsula foi menor no Grupo II. Conclusão: O laser de baixa intensidade altera o processo de reparação tecidual ao redor dos implantes, sugerindo que o mesmo possa ser útil para a modelação das contraturas que se estabelecem ao redor dos implantes de silicone. Descritores: Implantes de Mama. Terapia a Laser de Baixa Intensidade. Silicones. Rats.

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Breast augmentation

Farhadieh

Farhadi

2015

Plastic and Reconstructive Surgery

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The Composition and Behavior of Capsules around Smooth and Textured Breast Implants in Pigs

Cited by 56 publications

References 43 publications

Histological evaluation of capsules formed by silicon implants coated with polyurethane foam and with a textured surface in rats

Histological evaluation of capsules formed by silicon implants coated with polyurethane foam and with a textured surface in rats

Evaluation of low intensity laser's action on silicone mammary implant pseudocapsules in rats

Breast augmentation

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