The complications of mediastinal neural tumours

Parish, Christopher

doi:10.1016/0041-3879(70)90051-6

Cited by 2 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Clinical features of the nine cases are summarized in Table I. A review of the literature shows multiple reports of thoracic tumors in patients with NF1, primarily in adults [Manoli et al, 1969;Dines et al, 1966;Rutledge and Harolds, 1983;Stradling et al, 1981;Parish, 1971]. Thoracic tumors in NF most commonly arise from the chest wall, either from intercostal nerves or from sensory and sympathetic fibers supplying the pleura [Manoli et al, 1969].…”

Section: Discussionmentioning

confidence: 99%

Thoracic tumors in children with neurofibromatosis-1

et al. 1997

View full text Add to dashboard Cite

Thoracic tumors have been infrequently reported as a complication of neurofibromatosis-1 (NF1). To determine the prevalence and clinical features of thoracic tumors seen in children with NF1, we reviewed medical records and imaging studies for a group of 260 pediatric patients with NF1 followed in a multidisciplinary NF Center. Extrapleural thoracic tumors were seen in nine patients with NF1, corresponding to a prevalence of 3.5% in this hospital-based series of patients. Pathological studies of the tumors demonstrated plexiform neurofibroma in four cases and neurofibrosarcoma in one case. The remaining four cases were suspected to be plexiform neurofibroma based on clinical features but have not been confirmed histologically. Three patients presented with symptoms of chest pain, syncope, or wheezing; six patients were asymptomatic at the time of diagnosis of the tumors. Physical findings frequently found in patients with thoracic tumors were scoliosis (especially focal scoliosis) and visible plexiform neurofibromas of the neck. We conclude that NF1 patients presenting with any of these signs and symptoms should be screened for thoracic tumors with chest X-ray and magnetic resonance imaging as needed. It is unknown whether screening asymptomatic NF1 patients with chest X-rays on a regular basis will result in an improved outcome.

show abstract

Section: Discussionmentioning

confidence: 99%

Thoracic tumors in children with neurofibromatosis-1

et al. 1997

View full text Add to dashboard Cite

show abstract

“…Существует предположение, что ген NF1 входит в группу генов, подавляющих рост опухолей. Снижение или отсутствие выработки продукта гена -ней-рофибромина приводит к диспластической или неопластической пролиферации клеток [3,5,6].…”

unclassified

“…В зарубежной литературе [4][5][6][7][8] описаны случаи манифестирования этого заболевания с легочных проявлений, сочетанного или изолированного поражения легких и средостения. A. Baydur и соавт.…”

unclassified

Treatment of esophagopleural fistula in patient with lung and mediastinal neurofibromatosis

Drobyazgin¹,

Судовых²,

Chikinev³

2018

Endosk. khir.

View full text Add to dashboard Cite

The complications of mediastinal neural tumours

Cited by 2 publications

References 0 publications

Thoracic tumors in children with neurofibromatosis-1

Thoracic tumors in children with neurofibromatosis-1

Treatment of esophagopleural fistula in patient with lung and mediastinal neurofibromatosis

Contact Info

Product

Resources

About