The complications of enterocolitis

Latchis, Kenneth S; Rao, C. Shyam Sundar; Colcock, Bentley P.

doi:10.1016/0002-9610(71)90233-9

Cited by 14 publications

(7 citation statements)

References 32 publications

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“…Surgery carries risks, including mortality and POCs. Serious POCs, such as anastomotic leak and intra-abdominal sepsis, develop more frequently after surgery for CD than other intestinal resections [14, 15]. Incidence varies with the type of complication, as follows: 0%–18.8% for wound sepsis, 3.1%–18.7% for abdominal abscess, 0%–12.7% for anastomotic leak [8, 16, 17] and 0.6%–3.6% for post-operative death [17].…”

Section: Discussionmentioning

confidence: 99%

Perioperative management and early complications after intestinal resection with ileocolonic anastomosis in Crohn’s disease: analysis from the PRACTICROHN study

Gutiérrez

Rivero

Martín-Arranz³

et al. 2019

Gastroenterology Report

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Background This study is aimed at describing the prevalence of and risk factors associated with early post-operative complications after Crohn’s disease-related intestinal resection. Methods This was a retrospective analysis of data from the PRACTICROHN cohort. Adult Crohn’s disease patients who underwent ileocolonic resection with ileocolonic anastomosis between January 2007 and December 2010 were included. The complications evaluated included death, ileus, anastomotic leak, abscess, wound infection, catheter-related infection, digestive bleeding and other extra-abdominal infections that occurred in the 30 days after surgery. Results A total of 364 patients (median age at surgery 38 years and 50% men) were included. Indication for surgery was: stricturing disease (46.4%), penetrating disease (31.3%), penetrating and stricturing disease (14.0%) or resistance to medical treatment (5.8%). Early complications were recorded in 100 (27.5%) patients, with wound infection, intra-abdominal abscess and anastomotic leakage being the most frequent complications. Median hospitalization duration was 16 days for patients with complications vs. 9 days without complications ( P < 0.001). Complications were more common among patients with penetrating disease (36/114, 31.6%) and those refractory to treatment (9/21, 42.9%) compared with stricturing disease (45/169, 26.6%) or stricturing + penetrating disease (6/51, 11.8%) ( P = 0.040). The rate of complications was higher among patients with diagnosis made at the time of surgery (15/31, 48.4%) compared with the rest (85/331, 25.7%) ( P = 0.013). Medication received at the time of surgery did not affect the rate of complications. Conclusions Almost a quarter of patients developed early complications after intestinal resection. Penetrating disease and urgent surgery were associated with an increased risk of complications.

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Section: Discussionmentioning

confidence: 99%

Perioperative management and early complications after intestinal resection with ileocolonic anastomosis in Crohn’s disease: analysis from the PRACTICROHN study

Gutiérrez

Rivero

Martín-Arranz³

et al. 2019

Gastroenterology Report

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“…The septic complication rate after strictureplasty was similar or lower to that (3-50 percent) after bowel resection for Crohn_s disease. [82][83][84][85][86][87][88][89][90][91] Other complications included hemorrhage, ileus, wound infection, and bowel obstruction, but their incidence was low. Although major hemorrhage was rare, several patients, especially after multiple strictureplasties, required angiography to identify the bleeding site and intra-arterial vasopressin infusion.…”

Section: Jejunoileal Strictureplastymentioning

confidence: 96%

Safety and Efficacy of Strictureplasty for Crohn's Disease: A Systematic Review and Meta-Analysis

Yamamoto

Fazio

Tekkis

2007

Diseases of the Colon &Amp; Rectum

270

136

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“…No patient was on anti-TNF-a preoperatively. The risk factors and their frequencies [3,[5][6][7]11,[16][17][18][19]21] among the two groups are shown in Table 2. We also searched the database for details on blood loss during surgery, length of surgery and the need for blood transfusion.…”

Section: Patientsmentioning

confidence: 99%

“…Intestinal anastomoses in colorectal surgery are at risk of severe intra‐abdominal septic complications (IASC) as a result of dehiscence, fistula or abscess formation, which are associated with mortality [1]. In Crohn’s disease (CD) this risk is further increased by sepsis and malnutrition, caused by the disease, the immunosuppressive medication and the complexity of the surgery [2–5]. Previous reports have shown an increasing chance of anastomotic complications with an increasing number of risk factors [5–7].…”

Section: Introductionmentioning

confidence: 99%

Split stoma in resectional surgery of high‐risk patients with ileocolonic Crohn’s disease

Myrelid

Söderholm

Olaison³

et al. 2012

Colorectal Disease

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The complications of enterocolitis

Cited by 14 publications

References 32 publications

Perioperative management and early complications after intestinal resection with ileocolonic anastomosis in Crohn’s disease: analysis from the PRACTICROHN study

Perioperative management and early complications after intestinal resection with ileocolonic anastomosis in Crohn’s disease: analysis from the PRACTICROHN study

Safety and Efficacy of Strictureplasty for Crohn's Disease: A Systematic Review and Meta-Analysis

Split stoma in resectional surgery of high‐risk patients with ileocolonic Crohn’s disease

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