The Complications of Cardioembolic Stroke: Lessons from the VISTA Database

Hallevi, Hen; Albright, Karen C.; Martin‐Schild, Sheryl; Barreto, Andrew D; Grotta, James C.; Savitz, Sean I

doi:10.1159/000135651

Cited by 7 publications

(3 citation statements)

References 22 publications

(13 reference statements)

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“…The rate of recurrent stroke in patients with cardioembolism (1.6%) was threefold higher than that in patients with non-cardioembolic stroke (0.5%). Hallevi et al [11] found an even higher rate of recurrent stroke (2.5%) in their cohort of patients with cardioembolic stroke. Walter et al [29] identified an increased risk of pneumonia in cardioembolic stroke patients in comparison to those with lacunar infarction.…”

Section: Discussionmentioning

confidence: 83%

Evaluation of costs and outcome in cardioembolic stroke or TIA

et al. 2009

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The costs of acute stroke care, length of hospital stay (LOS), and outcome in patients with cardioembolic stroke or cardioembolic transient ischemic attacks (TIA) were investigated with the aim of estimating the clinical and health-economic impacts of cerebral cardioembolism. The study population consisted of 511 consecutive patients with the diagnosis of ischemic stroke (n = 379) or TIA (n = 132) treated at the Department of Neurology, Philipps University, Marburg. Cerebral cardioembolism was defined according to the criteria of the Cerebral Embolism Task Force. Clinical status was assessed by means of Barthel index (BI) and modified Rankin Scale. Costs were calculated using a bottom-up approach. All costs (in Euros) were inflated to the 2008 level. Compared to non-cardioembolic stroke (n = 278) patients, patients who had suffered cardioembolic stroke (n = 101) had more severe clinical deficits on admission (BI 46.3 +/- 27.0 vs. 59.3 +/- 34.1; P < 0.01), worse recovery (BI on discharge 59.2 +/- 28.9 vs. 73.1 +/- 33.4; P < 0.01), and increased LOS (12.6 +/- 5.7 vs. 10.0 +/- 7.8 days; P < 0.01). The latter also required a relatively higher daily resource utilization due to increased expenses for personnel and diagnostics. Mean costs of acute care for patients with cardioembolic stroke [euro 4890 per patient (95% confidence interval 4460-5200)] were significantly higher than those for patients with non-cardioembolic stroke [euro 3550 (95% confidence interval 3250-3850); P < 0.01]. The clinical and health-economic impact of cardiogenic cerebral embolism on stroke care is considerable. Patients with cardioembolic stroke/TIA are more severely impaired, and they require longer hospital treatment and increased resource utilization. Costs of acute care of cardioembolic stroke/TIA patients may exceed those of non-cardioembolic stroke/TIA by up to 40%.

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Section: Discussionmentioning

confidence: 83%

Evaluation of costs and outcome in cardioembolic stroke or TIA

et al. 2009

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“…Hallevi et al . (29) analysed 397 patients with cardioembolic stroke from the VISTA database who were not given thrombolytics. The mean age was 73 years and the mean NIHSS at admission was 14·3.…”

Section: Complications Of Cardioembolic Strokementioning

confidence: 99%

“…Cardioembolic strokes are responsible for about 20% of all strokes and tend to have a worse prognosis (28). Hallevi et al (29) analysed 397 patients with cardioembolic stroke from the VISTA database who were not given thrombolytics. The mean age was 73 years and the mean NIHSS at admission was 14·3.…”

Section: Complications Of Cardioembolic Strokementioning

confidence: 99%