Previous investigations of one-repetition maximum bench press (1 RM BP) performance have been either descriptive or have explored a limited number of contributing variables. The purpose of this study was to investigate the interplay between structural, technical and neuromuscular factors in relation to 1 RM BP in competitive powerlifters. Thirteen national and international level male powerlifters (26±9 years, 178±6 cm, 93.8±9.9 kg) visited the laboratory twice. Anthropometric and ultrasound measures were taken on the first visit, whereas performance measures (voluntary activation level, isokinetic strength, and kinetic, kinematic and electromyographic measurements during 1 RM BP) were recorded on the second visit. Correlation and multiple regression were used to investigate the contribution of structural, technical and neuromuscular variables to 1 RM BP corrected for body mass using the Wilks coefficient. The highest degree of association was shown for structural (lean and bone mass, brachial index, arm circumference and agonist cross-sectional area; r = 0.58-0.74) followed by neuromuscular factors (elbow and shoulder flexion strength; r = 0.57-0.71), whereas technical factors did not correlate with 1 RM BP performance (r ≤ 0.49). The multiple regression showed that lean body mass, brachial index and isometric shoulder flexion torque predicted 59% of the common variance in 1 RM BP. These data suggest that in a sample of elite competitive powerlifters, multiple factors contribute to 1 RM BP with variables such as lean body mass, the agonist cross-sectional area, brachial index, and strength of the elbow and shoulder flexors being the greatest predictors of performance.