2002
DOI: 10.1046/j.1365-2672.2002.01776.x
|View full text |Cite
|
Sign up to set email alerts
|

The complete nucleotide sequence of the Vibrio harveyi bacteriophage VHML

Abstract: Aims: To determine the complete nucleotide sequence of the bacteriophage VHML and establish a hypothesis for the virulence conversion caused by VHML infection of Vibrio harveyi. Methods and Results: The complete nucleotide sequence of VHML was determined (43 193 bp) and used to identify putative genes. The translated products of these genes were compared with reported sequences to assign hypothetical functions. All anticipated structural genes and putative genes for lysogeny were identified. In addition, we fo… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
105
0

Year Published

2004
2004
2022
2022

Publication Types

Select...
6
2
1

Relationship

0
9

Authors

Journals

citations
Cited by 84 publications
(105 citation statements)
references
References 27 publications
0
105
0
Order By: Relevance
“…Mortality caused by vibrios in reared fish and shellfish is very common during early larval stages and can occur suddenly, leading sometimes to death of the entire population (42,96,157,184,185,187,217,230,283,287,295). Pathogenicity of V. harveyi is associated with the presence of a bacteriophage (15,291). A bacteriological survey of cultures of sea bream (Sparus aurata L.) in Spain between 1997 and 2000 detected 25 outbreaks (450).…”
Section: Role In Aquaculturementioning
confidence: 99%
“…Mortality caused by vibrios in reared fish and shellfish is very common during early larval stages and can occur suddenly, leading sometimes to death of the entire population (42,96,157,184,185,187,217,230,283,287,295). Pathogenicity of V. harveyi is associated with the presence of a bacteriophage (15,291). A bacteriological survey of cultures of sea bream (Sparus aurata L.) in Spain between 1997 and 2000 detected 25 outbreaks (450).…”
Section: Role In Aquaculturementioning
confidence: 99%
“…15 We could not identify any previously characterized phages with ≥ 40% similarity that would belong to the same genus as ϕH111-1. Currently, phages with the most similar proteomes are AcaML1 of Acidithiobacillus caldus (JX507079.1; 28.17% similar) and the "Vhmllikevirus" phages VHML of Vibrio harveyi (NC_004456.1; 28.07% similar) and both [16][17][18][19] Although these phages share subfamily-level similarity, they are very distinct with respect to aspects such as host, gene content, and lifestyle. AcaML1 lysogenizes a thermophilic and acidophilic γ-proteobacterium and has a significantly larger 59 kbp genome with two insertion sequences.…”
Section: Sequence Analysismentioning
confidence: 99%
“…16 The "Vhmllikevirus" phages VHML, VP58.5, and vB_VpaM_MAR have similar genome sizes to ϕH111-1 (41-43 kbp) but are thought to lysogenize as linear plasmids with telomeres in Vibrio species. [17][18][19] The commonalities among ϕH111-1, AcaML1, and the "Vhmllikevirus" phages are largely restricted to the morphogenesis genes. These phages all have P2-like tail proteins, but encode capsid morphogenesis/DNA packaging and accessory proteins that are unrelated to those of P2 ( Table 2).…”
Section: Sequence Analysismentioning
confidence: 99%
“…Another myovirus, VHML of Vibrio harveyi (Oakey et al, 2002) that is closely related to one of the abovementioned phages, VP58.5 (Zabala et al, 2009) also contains genes encoding homologues of the N15-like protelomerase (Ravin, 2015) and partitioning protein ParA (Oakey et al, 2002). VHML was initially described as a prophage integrated into the host chromosome (Oakey et al, 2002), but later it was suggested that it may be a linear plasmid-like prophage as well (Lima-Mendez et al, 2008). VHML was recently included into the family of N15-like linear phage-plasmids (Ravin, 2015).…”
Section: Introductionmentioning
confidence: 99%