The complete mitochondrial genome of a purebred Tibetan Mastiff ( Canis lupus familiaris breed Tibetan Mastiff) from Lijiang, China, and comparison of genome-wide sequence variations

Abstract

In this study, the complete mitochondrial genome sequence of the Tibetan Mastiff was reported. The total length of the mitogenome is 16,729 bp. It contains the typical structure, including 13 protein-coding genes, 22 transfer RNA genes, 2 ribosomal RNA genes and 1 control region is in line with other canine animals. We further identified genome-wide variations among different canine mitochondrial genomes and indicated that the D-loop region harbors the most sequence variation, which will provide sequence variation information for the protection and utilization of the Tibetan Mastiff germplasm resource.