The Complementary Aspect in the Relation Between Biological and Psychodynamic Psychiatry

Praag, H. M. van

doi:10.1159/000278579

Cited by 4 publications

(4 citation statements)

References 7 publications

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“…Psychological interventions, then, will never be irrelevant in treating personality pathology [66][67][68][69].…”

Section: Psychotropic Drugs and Personality Disordermentioning

confidence: 99%

Inflationary Tendencies in Judging the Yield of Depression Research

Praag

1998

Neuropsychobiology

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The mood around mood disorders is one of optimism. Progress in diagnosis and treatment is generally felt to be considerable. Zeitgeist rests on convictions. In this case the main supporting convictions are the following: depression is a very frequent disorder and its diagnosis has improved greatly; we dispose of more or less specific agents to control depression: biological psychiatric research made great strides, particularly in the field of affective disorders; new antidepressants are properly tested before being clinically introduced. Each of these convictions is critically analysed. It is concluded that each of these claims is either a half-truth or not true. Apparently reality awareness and reality testing are out of balance. This harms the prospects of research, particularly biological research. Ways to avoid the stalemate are discussed.

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“…Psychological interventions, then, will never be irrelevant in treating personality pathology [66][67][68][69].…”

Section: Psychotropic Drugs and Personality Disordermentioning

confidence: 99%

Inflationary Tendencies in Judging the Yield of Depression Research

Praag

1998

Neuropsychobiology

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“…Mind as well as brain are both legitimate frameworks for the study of depression and the data so obtained are complementary rather than contradictory [37], Biologi cal variables pertain to pathogenesis, i.e. the conglomer ate of brain dysfunctions underlying the behavioral dis order.…”

Section: The Complementary Relation Between Psychological and Biologimentioning

confidence: 99%

“…Prolonged stress could conceivably lead to exhaustion of the CA-ergic system, in par ticular, if glucocorticoid receptors are hyposensitive and/or the anlage of tyrosine hydroxylase is marginal. Exhaustion of the CA-ergic system is possibly a factor un derlying depression [37,39,40]. sine hydroxylase, the enzyme accelerating the first step in the CA synthesis [review: [39][40][41], The CA system, however, is not inexhaustible, as has been demonstrated in animals subjected to inescapable stress [42].…”

Section: Causation Of Abnormal Behavior Etiological Factors Biologicamentioning

confidence: 99%

Moving Ahead Yet Falling Behind

Hm¹

1989

Neuropsychobiology

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The progress of psychiatry over the past few years is impressive. That process, however, is nonlinear and in this paper three developments in depression research are discussed and thought to be counterproductive. First, the depression classification as institutionalized by the DSM-III is an unfocused and confusing one. The regular revisions, moreover, largely based on the opinions of experts rather than on the research by experts, add to the confusion. Second, the preoccupation of biological psychiatry with nosology is seen as a growth-inhibiting factor. The functional/dimensional approach searching for correlations between biological and psychological dysfunctions, an approach we have been advocating for many years, seems to have great potential and deserves to be included in mainstream biological psychiatry. Finally, the ‘biologization’ of depression research went too far. The conception of depression as a brain disease is a ‘terrible simplification’, even for the syndrome considered to be the most ‘biological’ of all: major depression, melancholic type. Psychological determinants of the brain dysfunctions underlying depressive disorders deserve as much scientific scrutiny as their biological counterparts. Te mind should not be the soft belly of (biological) psychiatry.

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“…For this reason I wish to venture upon a comparison of the two therapies in terms of their objectives. My premise is that it is possible and meaningful to consider every mentally disturbed indi vidual from a threefold angle: the input aspect, the machinery aspect and the output aspect (61,63,65,66). I define input as the totality of pathogenic factors that influenced the individual recently or in the past and must be held responsible for the ultimate occurrence of the mental disturbances.…”

Section: The Objectives Of Pharmacotherapy and Psychotherapymentioning

confidence: 99%